| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3417877 | B | Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization assay | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 2. | ALA3417878 | B | Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 3. | ALA3417879 | B | Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 4. | ALA3417880 | F | Induction of apoptosis in wild-type MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3417881 | F | Induction of apoptosis in Bcl2-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA3417882 | F | Induction of apoptosis in Bad-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA3417883 | F | Induction of apoptosis in Bid-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA3417884 | F | Induction of apoptosis in Bak-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA3417885 | F | Induction of apoptosis in Bax-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3420567 | F | Induction of apoptosis in Bax/Bak-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing after 24 hrs by DAPI staining | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA3420575 | F | Induction of apoptosis in MEF assessed as appearance of cell membrane blebbing at 15 uM after 24 hrs by DAPI staining in presence of caspase inhibitor Ac-DEVD-CHO | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3420576 | B | Activation of Bax in human HuH7 cells assessed as inhibition of mitochondrial accumulation of fluorescent probe Mitotracker Red after 12 to 72 hrs by spectrophotometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA3420578 | B | Activation of Bax in human HuH7 cells assessed as conformational changes by SDS-PAGE analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3420579 | B | Induction of Bax translocation from cytoplasm to mitochondria in human HuH7 cells at 10 uM after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3420580 | B | Activation of Bax in human HuH7 cells assessed as cyt-C release from mitochondria by MitoTracker Red dye-based immunofluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3420581 | B | Activation of Bax in human HuH7 cells assessed as induction of caspase-3 activation at 10 uM by immunofluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3420582 | B | Activation of Bax in human HuH7 cells assessed as formation of apoptotic nuclei at 10 uM by immunofluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3420583 | B | Activation of Bax mutant in human Jurkat cells assessed as increase in apoptosis rate at 10 uM after 72 hrs by DAPI staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3420584 | B | Activation of Bax in human NB4 cells assessed as increase in apoptosis rate at 10 uM after 12 hrs by DAPI staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3420585 | A | Cytotoxicity against C57BL/6J mouse primary splenocytes assessed as effect on apoptosis rate at 10 uM after 72 hrs by DAPI staining | Mus musculus | 1 | cell-based format | Scientific Literature |
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