# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3417877 | Binding | Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization assay | Homo sapiens | 16 | ALA3414479 | assay format | Scientific Literature | |
2. | ALA3417878 | Binding | Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assay | Homo sapiens | 16 | ALA3414479 | assay format | Scientific Literature | |
3. | ALA3417879 | Binding | Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assay | Homo sapiens | 16 | ALA3414479 | assay format | Scientific Literature | |
4. | ALA3420568 | Functional | Induction of apoptosis in MEF assessed as appearance of fragmented nuclei and cell membrane blebbing at 15 uM after 24 hrs by DAPI staining | Mus musculus | 14 | ALA3414479 | cell-based format | Scientific Literature | |
5. | ALA3420574 | Functional | Induction of apoptosis in Bax/Bak-deficient MEF assessed as appearance of fragmented nuclei and cell membrane blebbing at 15 uM after 24 hrs by DAPI staining | Mus musculus | 14 | ALA3414479 | cell-based format | Scientific Literature |