# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3425152 | Binding | Antagonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli BL21 DE3 after 4 to 6 hrs by GFP reporter gene assay | Pseudomonas aeruginosa | 14 | ALA3421563 | assay format | Scientific Literature | |
2. | ALA3425153 | Binding | Antagonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli BL21 DE3 at 100 uM after 4 to 6 hrs by GFP reporter gene assay relative to Br-HSL | Pseudomonas aeruginosa | 11 | ALA3421563 | assay format | Scientific Literature | |
3. | ALA3425155 | Binding | Antagonist activity at LasR in Pseudomonas aeruginosa PAO1 assessed as decrease in pyocyanin level in cell-free supernatants after 12 hrs | Pseudomonas aeruginosa PAO1 | 1 | ALA3421563 | single protein format | Scientific Literature | |
4. | ALA3425158 | Binding | Irreversible antagonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli BL21 DE3 at 10 to 100 uM after 4 to 6 hrs by GFP reporter gene assay in presence of LasR agonist 3-oxo-C12HSL | Pseudomonas aeruginosa | 1 | ALA3421563 | assay format | Scientific Literature | |
5. | ALA3425160 | Binding | Antagonist activity at LasR in Pseudomonas aeruginosa PA14 assessed as decrease in pyocyanin level in cell-free supernatants after 12 hrs | Pseudomonas aeruginosa PA14 | 1 | ALA3421563 | single protein format | Scientific Literature | |
6. | ALA3425161 | Binding | Antagonist activity at LasR in Pseudomonas aeruginosa PAO1 assessed as decrease in pyocyanin level in extracted and acidified cell-free supernatants after 12 hrs | Pseudomonas aeruginosa PAO1 | 1 | ALA3421563 | single protein format | Scientific Literature | |
7. | ALA3425162 | Binding | Antagonist activity at LasR in Pseudomonas aeruginosa PA14 assessed as decrease in pyocyanin level in extracted and acidified cell-free supernatants after 12 hrs | Pseudomonas aeruginosa PA14 | 1 | ALA3421563 | single protein format | Scientific Literature | |
8. | ALA3425163 | ADME | Effect on growth of Pseudomonas aeruginosa PAO1 at 12.5 to 25 uM | Pseudomonas aeruginosa | 1 | ALA3421563 | organism-based format | Scientific Literature | |
9. | ALA3425164 | ADME | Effect on growth of Pseudomonas aeruginosa PA14 at 12.5 to 25 uM | Pseudomonas aeruginosa | 1 | ALA3421563 | assay format | Scientific Literature | |
10. | ALA3425165 | Binding | Antagonist activity at LasR in Pseudomonas aeruginosa PA14 assessed as inhibition of static biofilm formation after 48 hrs by crystal violet staining | Pseudomonas aeruginosa PA14 | 1 | ALA3421563 | single protein format | Scientific Literature | |
11. | ALA3425166 | Binding | Antagonist activity at LasR in Pseudomonas aeruginosa PA14 assessed as inhibition of static biofilm thickness grown in rich media after 36 hrs by SYTO-9 nucleic acid staining-based confocal microscopic analysis | Pseudomonas aeruginosa PA14 | 1 | ALA3421563 | single protein format | Scientific Literature | |
12. | ALA3425167 | Binding | Antagonist activity at LasR in Pseudomonas aeruginosa PA14 assessed as inhibition of overall static biofilm biomass grown in rich media after 36 hrs SYTO-9 nucleic acid staining-based confocal microscopic analysis | Pseudomonas aeruginosa PA14 | 1 | ALA3421563 | single protein format | Scientific Literature | |
13. | ALA3425205 | Binding | Antagonist activity at LasR in Pseudomonas aeruginosa PA14 assessed as inhibition of static biofilm biomass grown in defined media at 12.5 to 25 uM after 36 hrs SYTO-9 nucleic acid staining-based confocal microscopic analysis | Pseudomonas aeruginosa PA14 | 1 | ALA3421563 | single protein format | Scientific Literature | |
14. | ALA3425206 | Binding | Antagonist activity at LasR in Pseudomonas aeruginosa PA14 assessed as inhibition of static biofilm thickness grown in defined media at 12.5 to 25 uM after 36 hrs SYTO-9 nucleic acid staining-based confocal microscopic analysis | Pseudomonas aeruginosa PA14 | 1 | ALA3421563 | single protein format | Scientific Literature | |
15. | ALA3425207 | Binding | Antagonist activity at LasR in Pseudomonas aeruginosa PA14 assessed as inhibition of overall static biofilm morphology grown in defined media at 12.5 to 25 uM after 36 hrs SYTO-9 nucleic acid staining-based confocal microscopic analysis | Pseudomonas aeruginosa PA14 | 1 | ALA3421563 | single protein format | Scientific Literature |