# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3425211 | B | Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex red assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
2. | ALA3425212 | B | Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by luminescence assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
3. | ALA3425214 | B | Inhibition of human recombinant MAOB expressed in Pichia pastoris at 100 uM incubated for 15 mins prior to substrate addition measured after 30 mins by luminescence assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
4. | ALA3425215 | B | Selectivity index, ratio of IC50 for human recombinant MAOA to IC50 for human recombinant LSD1 | Homo sapiens | 4 | assay format | Scientific Literature | ||
5. | ALA3425219 | F | Induction of Gfi-1b gene expression in human NB4 cells at IC50 after 24 hrs by RT-PCR analysis relative to vehicle-treated control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
6. | ALA3425220 | F | Induction of ITGAM gene expression in human NB4 cells at IC50 after 24 hrs by RT-PCR analysis relative to vehicle-treated control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA3425221 | F | Inhibition of colony formation in mouse acute promyelocytic leukemic cell at 0.25 uM after 7 days by colony forming unit assay | Mus musculus | 3 | assay format | Scientific Literature |