# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3425138 | B | Inhibition of recombinant human PFKFB1 using fructose 6 phosphate as substrate assessed as ADP generation after 1 hr by ADP Glo assay | Homo sapiens | 37 | single protein format | Scientific Literature | ||
2. | ALA3425139 | B | Inhibition of recombinant human PFKFB2 using fructose 6 phosphate as substrate assessed as ADP generation after 1 hr by ADP Glo assay | Homo sapiens | 37 | single protein format | Scientific Literature | ||
3. | ALA3425140 | B | Inhibition of recombinant human PFKFB3 using fructose 6 phosphate as substrate assessed as ADP generation after 1 hr by ADP Glo assay | Homo sapiens | 38 | single protein format | Scientific Literature | ||
4. | ALA3425141 | P | Lipophilicity, log D of the compound at pH 7.4 | 35 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA3425231 | B | Inhibition of PFKFB3 in human A549 cells assessed as reduction of fructose-1,6-bisphosphate formation after 4 hrs by MS/MS analysis | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
6. | ALA3425232 | B | Inhibition of PFKFB3 in human A549 cells assessed as decrease in lactate secretion after 4 hrs | Homo sapiens | 32 | cell-based format | Scientific Literature |