| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3424997 | B | Displacement of [3H]-SB222200 from recombinant human NK3R expressed in CHO cell membranes after 90 mins by scintillation counting analysis | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 2. | ALA3424998 | F | Antagonist activity at recombinant human NK3R expressed in CHO cells assessed as inhibition of NKB-induced Ca2+ signaling by aequorin Ca2+ bioluminescence assay | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 3. | ALA3424999 | P | Lipophilicity, log D of the compound at pH 7.4 | 19 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA3425000 | P | Solubility of the compound in PBS buffer at pH 7.4 by shake-flask method | 36 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA3425001 | A | Inhibition of CYP3A4 (unknown origin) by luciferase reporter assay in presence of NADPH regeneration system | Homo sapiens | 16 | single protein format | Scientific Literature | ||
| 6. | ALA3425002 | A | Inhibition of CYP2D6 (unknown origin) by luciferase reporter assay in presence of NADPH regeneration system | Homo sapiens | 17 | single protein format | Scientific Literature | ||
| 7. | ALA3425003 | A | Inhibition of CYP2C9 (unknown origin) by luciferase reporter assay in presence of NADPH regeneration system | Homo sapiens | 17 | single protein format | Scientific Literature | ||
| 8. | ALA3425004 | A | Inhibition of CYP2C19 (unknown origin) by luciferase reporter assay in presence of NADPH regeneration system | Homo sapiens | 17 | single protein format | Scientific Literature | ||
| 9. | ALA3425005 | A | Inhibition of CYP1A2 (unknown origin) by luciferase reporter assay in presence of NADPH regeneration system | Homo sapiens | 17 | single protein format | Scientific Literature | ||
| 10. | ALA3425006 | B | Inhibition of human ERG expressed in HEK293 cells after 5 mins by patch-clamp assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 11. | ALA3425007 | B | Displacement of [3H]-SB222200 from monkey NK3R after 90 mins by scintillation counting analysis | Macaca mulatta | 9 | single protein format | Scientific Literature | ||
| 12. | ALA3425008 | B | Displacement of [3H]-SB222200 from rat NK3R after 90 mins by scintillation counting analysis | Rattus norvegicus | 9 | single protein format | Scientific Literature | ||
| 13. | ALA3425009 | B | Displacement of [3H]-Substance P from human NK1R after 90 mins by scintillation counting analysis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 14. | ALA3425010 | B | Displacement of [125I]-neurokinin A from human NK2R after 90 mins by scintillation counting analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 15. | ALA3425011 | B | Inhibition of GPR54 (unknown origin) at 10 uM relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 16. | ALA3425012 | B | Inhibition of KOR (unknown origin) at 10 uM relative to control | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 17. | ALA3425013 | B | Inhibition of GnRH-R (unknown origin) at 10 uM relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 18. | ALA3425014 | B | Inhibition of NPFF1 (unknown origin) at 10 uM relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 19. | ALA3425067 | A | Fraction unbound in rat plasma at 5 uM after 4 hrs by equilibrium dialysis method | Rattus norvegicus | 7 | cell-free format | Scientific Literature | ||
| 20. | ALA3425173 | A | Apparent permeability across apical to basolateral side in human Caco2 cells in presence of 0.1% bovine serum albumin | Homo sapiens | 6 | cell-based format | Scientific Literature |
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