# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3424219 | B | Inhibition of human 11beta-HSD1 overexpressed in microsomal fraction of HEK293 cells assessed as formation of [3H]-cortisol from [3H]-cortisone by scintillation proximity assay in presence of NADPH | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA3424220 | B | Inhibition of mouse 11beta-HSD2 overexpressed in microsomal fraction of HEK293 cells using [3H]-cortisol as substrate by scintillation proximity assay in presence of NAD+ | Mus musculus | 6 | cell-based format | Scientific Literature | ||
3. | ALA3424221 | B | Inhibition of mouse 11beta-HSD1 overexpressed in microsomal fraction of HEK293 cells assessed as formation of [3H]-cortisol from [3H]-cortisone by scintillation proximity assay in presence of NADPH | Mus musculus | 6 | cell-based format | Scientific Literature | ||
4. | ALA3424222 | B | Selectivity ratio of IC50 for human 11beta-HSD2 to IC50 for human 11beta-HSD1 | Homo sapiens | 6 | assay format | Scientific Literature | ||
5. | ALA3424223 | B | Inhibition of human 11beta-HSD2 overexpressed in microsomal fraction of HEK293 cells using [3H]-cortisol as substrate by scintillation proximity assay in presence of NAD+ | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
6. | ALA3424224 | B | Selectivity ratio of IC50 for mouse 11beta-HSD2 to IC50 for mouse 11beta-HSD1 | Mus musculus | 6 | assay format | Scientific Literature | ||
7. | ALA4011314 | F | Cytotoxicity against human KB cells assessed as growth inhibition after 72 hrs by neutral red assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
8. | ALA4011315 | F | Cytotoxicity against human Lu1 cells assessed as growth inhibition after 72 hrs by neutral red assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
9. | ALA4011316 | F | Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by neutral red assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
10. | ALA4011317 | F | Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by neutral red assay | Homo sapiens | 16 | cell-based format | Scientific Literature |