| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3424031 | B | Inhibition of recombinant FDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using GPP and [14C]IPP as substrate treated with enzyme for 10 mins prior to substrate challenge for 30 mins by liquid scintillation counting analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 2. | ALA3424032 | B | Inhibition of recombinant GGTase 2 (unknown origin) using recombinant Rab1A and [3H]GGPP as substrate after 20 mins in presence of recombinant REP-2 by liquid scintillation counting analysis | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 3. | ALA3424033 | B | Inhibition of GGTase 1 in human RPMI8226 cells assessed as unmodified Rap1a accumulation at 5 mM incubated for 48 hrs by immunoblot method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA3424034 | B | Inhibition of GGTase 2 in human RPMI8226 cells assessed as reduction in membrane bound Rab6 protein at 5 mM incubated for 48 hrs by immunoblot method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA3424040 | B | Inhibition of GGTase 2 in human RPMI8226 cells assessed as disruption of monoclonal protein trafficking by measuring accumulation of intracellular lambda light chain at 5 mM incubated for 48 hrs by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature |
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