| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3423870 | F | Antagonist activity at human mGluR1 expressed in human Chem-3 cells assessed as inhibition of L-glutamate-induced calcium release at 10 uM by calcium-5 reagent-based fluorescence assay relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 2. | ALA3423871 | F | Antagonist activity at human mGluR5 expressed in human embryonic kidney cells assessed as inhibition of L-glutamate-induced calcium release at 10 uM by calcium-5 reagent-based fluorescence assay relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 3. | ALA3423872 | F | Antagonist activity at human mGluR1 expressed in human Chem-3 cells assessed as inhibition of L-glutamate-induced calcium release by calcium-5 reagent-based fluorescence assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 4. | ALA3423873 | F | Antagonist activity at human mGluR5 expressed in human embryonic kidney cells assessed as inhibition of L-glutamate-induced calcium release by calcium-5 reagent-based fluorescence assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 5. | ALA3423874 | A | Inhibition of recombinant human CYP1A2 assessed as remaining activity at 10 uM preincubated for 5 mins followed by substrate and NADP addition measured after 20 mins by fluorescence assay relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 6. | ALA3423875 | A | Inhibition of recombinant human CYP2D6 assessed as remaining activity at 10 uM preincubated for 5 mins followed by substrate and NADP addition measured after 20 mins by fluorescence assay relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 7. | ALA3423876 | A | Inhibition of recombinant human CYP2C9 assessed as remaining activity at 10 uM preincubated for 5 mins followed by substrate and NADP addition measured after 20 mins by fluorescence assay relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 8. | ALA3423877 | A | Inhibition of recombinant human CYP3A4 assessed as remaining activity at 10 uM preincubated for 5 mins followed by substrate and NADP addition measured after 20 mins by fluorescence assay relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 9. | ALA3423878 | A | Inhibition of recombinant human CYP2C19 assessed as remaining activity at 10 uM preincubated for 5 mins followed by substrate and NADP addition measured after 20 mins by fluorescence assay relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 10. | ALA3423879 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 1 uM after 30 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 11. | ALA3423880 | B | Agonist activity at 5HT2A receptor (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA3423881 | B | Agonist activity at 5HT2C receptor (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA3423882 | B | Agonist activity at ADRA1A (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA3423883 | B | Agonist activity at BDKR2 (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA3423884 | B | Agonist activity at CB1 receptor (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3423885 | B | Agonist activity at CCR2B (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA3423913 | B | Agonist activity at CCR4 (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA3423914 | B | Agonist activity at CCR5 (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA3423915 | B | Agonist activity at CXCR2 (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA3423916 | B | Agonist activity at CXCR4 (unknown origin) at 12.5 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |
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