| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3429503 | B | Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as substrate/cofactor preincubated for 2 hrs followed by dopamine/SAM addition after 25 mins by fluorescence polarization assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 2. | ALA3429504 | B | Inhibition of recombinant rat membrane bound COMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL using dopamine/SAM as substrate/cofactor preincubated for 2 hrs followed by dopamine/SAM addition after 25 mins by fluorescence polarization assay | Rattus norvegicus | 13 | assay format | Scientific Literature | ||
| 3. | ALA3429505 | B | Inhibition of recombinant human soluble COMT using dopamine/SAM as substrate/cofactor preincubated for 2 hrs followed by dopamine/SAM addition after 25 mins by fluorescence polarization assay | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 4. | ALA3429507 | A | Ratio of tolcapone activity to compound activity for disruption of Sprague-Dawley rat heart mitochondrial membrane potential | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
| 5. | ALA3429508 | A | Ratio of entacapone activity to compound activity for disruption of Sprague-Dawley rat heart mitochondrial membrane potential | Rattus norvegicus | 3 | assay format | Scientific Literature |
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