#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3429503	Binding	Inhibition of C-terminal His6-tagged recombinant human membrane bound COMT expressed in Bacmid infected Sf-9 insect cells using dopamine/SAM as substrate/cofactor preincubated for 2 hrs followed by dopamine/SAM addition after 25 mins by fluorescence polarization assay	Homo sapiens	26	ALA3425416	cell-based format	Scientific Literature
2.	ALA3429504	Binding	Inhibition of recombinant rat membrane bound COMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL using dopamine/SAM as substrate/cofactor preincubated for 2 hrs followed by dopamine/SAM addition after 25 mins by fluorescence polarization assay	Rattus norvegicus	13	ALA3425416	assay format	Scientific Literature
3.	ALA3429505	Binding	Inhibition of recombinant human soluble COMT using dopamine/SAM as substrate/cofactor preincubated for 2 hrs followed by dopamine/SAM addition after 25 mins by fluorescence polarization assay	Homo sapiens	13	ALA3425416	single protein format	Scientific Literature
4.	ALA3429507	ADME	Ratio of tolcapone activity to compound activity for disruption of Sprague-Dawley rat heart mitochondrial membrane potential	Rattus norvegicus	3	ALA3425416	assay format	Scientific Literature
5.	ALA3429508	ADME	Ratio of entacapone activity to compound activity for disruption of Sprague-Dawley rat heart mitochondrial membrane potential	Rattus norvegicus	3	ALA3425416	assay format	Scientific Literature