| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3428330 | B | Binding affinity to 5'-end biotinylated ADAM10 A10-RNA QGRS (unknown origin) by surface plasmon resonance assay method | Not specified | 32 | assay format | Scientific Literature | ||
| 2. | ALA3428331 | B | Binding affinity to ADAM10 A10-RNA QGRS (unknown origin) assessed as increase in RNA-ligand complexes at 0.5 to 10 fold excess compound level by native gel electrophoresis method | Not specified | 1 | assay format | Scientific Literature | ||
| 3. | ALA3428332 | B | Binding affinity to ADAM10 A10-RNA QGRS (unknown origin) assessed as reduction in RNA G-quadruplex bands at 0.5 to 10 fold excess compound level by native gel electrophoresis method | Not specified | 1 | assay format | Scientific Literature | ||
| 4. | ALA3428333 | B | Binding affinity to ADAM10 A10-mutant RNA QGRS (unknown origin) by microscale thermophoresis method | Not specified | 1 | assay format | Scientific Literature | ||
| 5. | ALA3428334 | B | Binding affinity to ADAM10 A10-RNA QGRS (unknown origin) by microscale thermophoresis method | Not specified | 1 | assay format | Scientific Literature | ||
| 6. | ALA3428335 | B | Binding affinity to ADAM10 A10-RNA QGRS (unknown origin) transfected in human HeLa cells assessed as increase in ADAM10 translation efficiency at 2 uM after 24 hrs by Renilla/firefly dual luciferase reporter assay | Not specified | 11 | cell-based format | Scientific Literature | ||
| 7. | ALA3428336 | T | Toxicity against APP expressing HEK cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 8. | ALA3428337 | T | Toxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 9. | ALA3428338 | B | Binding affinity to 5'-end biotinylated ADAM10 A10-mutant RNA QGRS (unknown origin) by surface plasmon resonance assay method | Not specified | 32 | assay format | Scientific Literature | ||
| 10. | ALA3428339 | B | Effect on secondary structure of ADAM10 A10-RNA QGRS (unknown origin) by CD spectroscopy | Not specified | 1 | assay format | Scientific Literature | ||
| 11. | ALA3428340 | T | Toxicity against human HeLa cells assessed as effect on cell number at 0.5 to 2.5 uM after 24 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3428341 | T | Toxicity against human HeLa cells assessed as effect on cell morphology at 0.5 to 2.5 uM after 24 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3428342 | B | Binding affinity to ADAM10 A10-RNA QGRS (unknown origin) transfected in human HeLa cells assessed as increase in ADAM10 translation efficiency at 0.5 to 2.5 uM after 24 hrs by Renilla/firefly dual luciferase reporter assay | Not specified | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA3428343 | B | Binding affinity to ADAM10 A10-RNA QGRS (unknown origin) transfected in human HeLa cells assessed as increase in ADAM10 translation efficiency at 0.5 uM after 24 hrs by Renilla/firefly dual luciferase reporter assay | Not specified | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3428344 | B | Binding affinity to ADAM10 A10-RNA QGRS (unknown origin) transfected in human HeLa cells assessed as increase in ADAM10 translation efficiency at 1 uM after 24 hrs by Renilla/firefly dual luciferase reporter assay | Not specified | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3428345 | B | Binding affinity to ADAM10 A10-RNA QGRS (unknown origin) transfected in human HeLa cells assessed as increase in ADAM10 translation efficiency at 2.5 uM after 24 hrs by Renilla/firefly dual luciferase reporter assay | Not specified | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3428346 | B | Binding affinity to ADAM10 A10-mutant RNA QGRS (unknown origin) transfected in human HeLa cells assessed as increase in ADAM10 translation efficiency at 0.5 to 2.5 uM after 24 hrs by Renilla/firefly dual luciferase reporter assay | Not specified | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3428347 | B | Binding affinity to ADAM10 5'-UTR mutant RNA QGRS (unknown origin) transfected in human HeLa cells assessed as increase in ADAM10 translation efficiency at 0.5 uM after 24 hrs by Renilla/firefly dual luciferase reporter assay | Not specified | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3428348 | B | Binding affinity to ADAM10 A10-RNA QGRS (unknown origin) transfected in human HeLa cells assessed as increase in luciferase mRNA expression at 0.5 to 2.5 uM after 24 hrs by RT-PCR method | Not specified | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3428349 | B | Binding affinity to ADAM10 A10-mutant RNA QGRS (unknown origin) transfected in human HeLa cells assessed as increase in luciferase mRNA expression at 0.5 to 2.5 uM after 24 hrs by RT-PCR method | Not specified | 1 | cell-based format | Scientific Literature |
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