# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3429681 | F | Antiviral activity against dengue virus 2 infected in BHK21 cells incubated for 48 hrs by CFI assay | dengue virus type 2 | 26 | organism-based format | Scientific Literature | ||
2. | ALA3429682 | F | Antiviral activity against dengue virus 2 infected in human A549 cells incubated for 48 hrs by viral titer reduction assay | dengue virus type 2 | 2 | organism-based format | Scientific Literature | ||
3. | ALA3429683 | A | Cytotoxicity against human HepG2 cells incubated for 96 hrs by CCK8 assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
4. | ALA3429684 | P | Solubility in pH 6.5 buffer | 4 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA3429685 | P | Lipophilicity, log P of the compound | 4 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA3429686 | A | Hepatic extraction ratio in mouse liver microsomes | Mus musculus | 4 | assay format | Scientific Literature | ||
7. | ALA3429687 | A | Half life in mouse liver microsomes | Mus musculus | 4 | assay format | Scientific Literature | ||
8. | ALA3429688 | A | Cmax in Wistar rat at 25 mg/kg, po after 0.17 to 24 hrs by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
9. | ALA3429689 | A | Tmax in Wistar rat at 25 mg/kg, po after 0.17 to 24 hrs by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
10. | ALA3429690 | A | AUC (0 to 24 hrs) in Wistar rat at 25 mg/kg, po after 0.17 to 24 hrs by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
11. | ALA3429691 | A | Absolute oral bioavailability in Wistar rat at 25 mg/kg after 0.17 to 24 hrs by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
12. | ALA3429692 | A | Volume of distribution at steady state in Wistar rat at 25 mg/kg, po after 0.17 to 24 hrs by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
13. | ALA3429693 | A | Plasma clearance in Wistar rat at 25 mg/kg, po after 0.17 to 24 hrs by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
14. | ALA3429694 | A | Terminal half-life in Wistar rat at 25 mg/kg, po after 0.17 to 24 hrs by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
15. | ALA4431566 | F | Antiviral activity against Dengue virus 2 NGC infected in HeLa cells assessed as reduction in viral RNA replication after 48 hrs by luciferase assay | dengue virus type 2 | 1 | organism-based format | Scientific Literature | ||
16. | ALA4431567 | F | Antiviral activity against Dengue virus 1 West Pacific infected in human A549 cells assessed as reduction in viral titer after 48 hrs by plaque assay | dengue virus type 1 | 1 | organism-based format | Scientific Literature | ||
17. | ALA4431568 | F | Antiviral activity against Dengue virus 2 NGC infected in human A549 cells assessed as reduction in viral titer after 48 hrs by plaque assay | dengue virus type 2 | 1 | organism-based format | Scientific Literature | ||
18. | ALA4431569 | F | Antiviral activity against Dengue virus 3 34640 infected in human A549 cells assessed as reduction in viral titer after 48 hrs by plaque assay | dengue virus type 3 | 1 | organism-based format | Scientific Literature | ||
19. | ALA4431570 | F | Antiviral activity against Dengue virus 4 22713 infected in BHK21 cells assessed as reduction in viral titer after 48 hrs by plaque assay | dengue virus type 4 | 1 | organism-based format | Scientific Literature | ||
20. | ALA4431571 | F | Antiviral activity against Hepatitis C virus genotype 1b infected in Huh7.5 cells assessed as reduction in viral replication after 48 hrs by Bright-Glo luciferase assay | Hepacivirus hominis | 1 | organism-based format | Scientific Literature |