| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3428376 | B | Inhibition of HDAC1/HDAC2 in human HeLa cells using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 2. | ALA3428377 | F | Cytotoxicity against human HEL cells assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 3. | ALA3428378 | F | Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 4. | ALA3428379 | F | Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 5. | ALA3428380 | F | Cytotoxicity against human U937 cells assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 6. | ALA3428381 | F | Cytotoxicity against human 3AO cells assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 7. | ALA3428382 | F | Cytotoxicity against human MDA cells assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 8. | ALA3428383 | F | Cytotoxicity against human ES2 cells assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 9. | ALA3428384 | F | Cytotoxicity against human KG1 cells assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 10. | ALA3428385 | A | Cytotoxicity against HUVEC assessed as growth inhibition after 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3428387 | F | Induction of nitric oxide release in human HEL cells at 100 uM after 3 to 5 hrs by Griess assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 12. | ALA3428388 | F | Cytotoxicity against hemoglobin treated human HEL cells assessed as growth inhibition at 2 uM treated for 24 hrs post hemoglobin challenge measured after 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3428389 | F | Induction of apoptosis in human HEL cells after 24 hrs by 7-AAD-annexin-V/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3428531 | F | Cell cycle arrest in human HEL cells assessed as accumulation at G1 phase at 0.5 uM after 48 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 47.87%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA3428532 | F | Cell cycle arrest in human HEL cells assessed as accumulation at G2 phase at 0.5 uM after 48 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 5.28%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA3428533 | F | Cell cycle arrest in human HEL cells assessed as accumulation at S phase at 0.5 uM after 48 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 46.88%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA3428534 | F | Antitumor activity against human HEL cells xenografted in BALB/c-nu mouse assessed as inhibition of tumor growth at 120 mg/kg/day, po administered for 21 days measured every 3 days during compound dosing relative to control | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA3428535 | F | Antitumor activity against human HEL cells xenografted in BALB/c-nu mouse assessed as inhibition of tumor growth at 100 mg/kg/day, po administered for 21 days measured every 3 days during compound dosing relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA3428536 | F | Antitumor activity against human HEL cells xenografted in BALB/c-nu mouse assessed as decrease in tumor volume at 120 mg/kg/day, po administered for 21 days measured every 3 days during compound dosing relative to control | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA3428537 | F | Antitumor activity against human HEL cells xenografted in BALB/c-nu mouse assessed as decrease in tumor volume at 100 mg/kg/day, po administered for 21 days measured every 3 days during compound dosing relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature |
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