#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3430052	B	Displacement of [3H]TBPS from GABAA receptor in Sprague-Dawley rat brain cortical membrane after 90 mins by liquid scintillation spectrometry	Rattus norvegicus	32	ALA3425450	assay format	Scientific Literature
2.	ALA3430053	B	Positive allosteric modulation of recombinant alpha1beta2gamma2 GABAA receptor (unknown origin) expressed in LTK cells assessed as potentiation of GABA-induced channel current treated for 30 s prior to GABA stimulation for 2s by Q-patch assay	Homo sapiens	30	ALA3425450	cell-based format	Scientific Literature
3.	ALA3427979	P	Retention time of the compound by LC-MS analysis		28	ALA3425450	small-molecule physicochemical format	Scientific Literature
4.	ALA3427980	B	Positive allosteric modulation of recombinant alpha4beta3delta GABAA receptor (unknown origin) expressed in CHO cells assessed as potentiation of GABA-induced channel current treated for 30 s prior to GABA stimulation for 2s by manual patch assay	Homo sapiens	30	ALA3425450	cell-based format	Scientific Literature
5.	ALA4040853	B	Displacement of [35S]TBPS from GABA-A receptor in Sprague-Dawley rat cerebral cortex cell membranes after 90 mins in presence of GABA by liquid scintillation counting	Rattus norvegicus	21	ALA4038335	assay format	Scientific Literature
6.	ALA4040854	B	Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-mediated increase in channel current under holding potential at -80 mV preincubated for 30 secs followed by GABA stimulation for 2 secs by automated patch clamp assay	Homo sapiens	21	ALA4038335	cell-based format	Scientific Literature
7.	ALA4040855	B	Positive allosteric modulation of GABAA receptor alpha1beta2gamma2 (unknown origin) expressed in mouse LTK cells assessed as potentiation of GABA-mediated increase in channel current under holding potential at -80 mV at 0.01 to 10 uM preincubated for 30 secs followed by GABA stimulation for 2 secs by automated patch clamp assay relative to GABA	Homo sapiens	21	ALA4038335	cell-based format	Scientific Literature
8.	ALA4040856	B	Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated increase in channel current under holding potential at -80 mV preincubated for 30 secs followed by GABA stimulation for 2 secs by manual patch clamp assay	Homo sapiens	21	ALA4038335	cell-based format	Scientific Literature
9.	ALA4040857	B	Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated increase in channel current under holding potential at -80 mV at 0.01 to 10 uM preincubated for 30 secs followed by GABA stimulation for 2 secs by manual patch clamp assay relative to GABA	Homo sapiens	21	ALA4038335	cell-based format	Scientific Literature
10.	ALA4040858	P	Lipophilicity, logD of compound at 20 uM at pH 7.4 by HPLC/MS-MS analysis		7	ALA4038335	small-molecule physicochemical format	Scientific Literature
11.	ALA4040859	P	Thermodynamic aqueous solubility of compound at 10 uM sonicated for 1 min followed by incubation for 1 hr by HPLC-MS/MS		7	ALA4038335	small-molecule physicochemical format	Scientific Literature
12.	ALA4040860	A	Clearance in human hepatic microsomes at 10 uM preincubated for 5 mins followed by NADPH addition measured over 60 mins by HPLC-MS/MS analysis	Homo sapiens	7	ALA4038335	assay format	Scientific Literature
13.	ALA4040861	A	Clearance in rat hepatic microsomes at 10 uM preincubated for 5 mins followed by NADPH addition measured over 60 mins by HPLC-MS/MS analysis	Rattus norvegicus	7	ALA4038335	assay format	Scientific Literature
14.	ALA4040862	A	Clearance in mouse hepatic microsomes at 10 uM preincubated for 5 mins followed by NADPH addition measured over 60 mins by HPLC-MS/MS analysis	Mus musculus	7	ALA4038335	assay format	Scientific Literature
15.	ALA4040863	A	Clearance in Sprague-Dawley rat at 5 mg/kg, iv or 20 mg/kg, po measured up to 8 hrs post dose by LC/MS-MS analysis	Rattus norvegicus	7	ALA4038335	organism-based format	Scientific Literature
16.	ALA4040864	A	Clearance in CD1 mouse at 5 mg/kg, iv or 20 mg/kg, po measured up to 8 hrs post dose by LC/MS-MS analysis	Mus musculus	7	ALA4038335	organism-based format	Scientific Literature
17.	ALA4040865	A	Oral bioavailability in Sprague-Dawley rat at 20 mg/kg measured up to 8 hrs post dose by LC/MS-MS analysis	Rattus norvegicus	7	ALA4038335	organism-based format	Scientific Literature
18.	ALA4040866	A	Oral bioavailability in CD1 mouse at 20 mg/kg measured up to 8 hrs post dose by LC/MS-MS analysis	Mus musculus	7	ALA4038335	organism-based format	Scientific Literature
19.	ALA4040867	A	Ratio of drug level in Sprague-Dawley rat brain to plasma at 5 mg/kg, iv measured at 30 mins post dose by LC/MS-MS analysis	Rattus norvegicus	7	ALA4038335	organism-based format	Scientific Literature
20.	ALA4040868	A	Ratio of drug level in CD1 mouse brain to plasma at 5 mg/kg, iv measured at 30 mins post dose by LC/MS-MS analysis	Mus musculus	7	ALA4038335	organism-based format	Scientific Literature