# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA876076 | F | In vivo inhibition of antigen induced eosinophil recruitment in Brown-Norvway Rats at 10 mg/kg peroral dose | Rattus norvegicus | 14 | ALA1133554 | organism-based format | Scientific Literature | |
2. | ALA666906 | F | Emetic effect in dogs administered at 3 mg/kg intravenously (no effect) | Canis lupus familiaris | 1 | ALA1132852 | organism-based format | Scientific Literature | |
3. | ALA682878 | F | PDE4-related emetic activity in ferrets after intravenous administration at 10 mg/kg | Mustela putorius furo | 5 | ALA1133554 | organism-based format | Scientific Literature | |
4. | ALA758788 | B | Inhibition of phosphodiesterase 3 (PDE3) isolated from the dog aorta | Canis lupus familiaris | 36 | ALA1133554 | protein format | Scientific Literature | |
5. | ALA757136 | B | Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line. | 37 | ALA1133554 | cell-based format | Scientific Literature | ||
6. | ALA760946 | B | Inhibition of phosphodiesterase 1/5 isozyme (PDE1/5) mixture isolated from the guinea pig trachea. | Cavia porcellus | 35 | ALA1133554 | tissue-based format | Scientific Literature | |
7. | ALA760947 | B | Inhibitory activity against phosphodiesterase 1/5 (PDE1/5) extracted from guinea pig trachea smooth muscle cells by using radioligands [3H]-cAMP or [3H]cGMP | Cavia porcellus | 17 | ALA1132852 | tissue-based format | Scientific Literature | |
8. | ALA764838 | B | Inhibition of Phosphodiesterase 3 extracted from dog aorta smooth muscle cells by using radioligands [3H]cAMP or [3H]-cGMP. | Canis lupus familiaris | 21 | ALA1132852 | assay format | Scientific Literature | |
9. | ALA769674 | B | Inhibition of phosphodiesterase 4 | Homo sapiens | 7 | ALA1147448 | protein format | Scientific Literature | |
10. | ALA769677 | B | Inhibition of phosphodiesterase 4 extracted from human U937 cells by using radioligands [3H]-cAMP or [3H]cGMP. | 21 | ALA1132852 | cell-based format | Scientific Literature | ||
11. | ALA781248 | F | Inhibition of antigen-induced lung eosinophilia in ovalbumin sensitized brown-norway rats after oral administration | Rattus norvegicus | 1 | ALA1132852 | organism-based format | Scientific Literature | |
12. | ALA784398 | B | Binding affinity against high affinity rolipram binding site (HARBS) was determined by displacing radioactive [3H]rolipram from brain membrane suspensions of Wistar rats | 11 | ALA1132852 | assay format | Scientific Literature | ||
13. | ALA817437 | F | In vitro inhibition of TNF-alpha release from human peripheral blood monocytes | 12 | ALA1133554 | assay format | Scientific Literature | ||
14. | ALA817438 | F | In vitro inhibition of TNF-alpha-release from human whole blood | 14 | ALA1133554 | assay format | Scientific Literature | ||
15. | ALA817441 | F | In vivo inhibition of LPS-stimulated TNF-alpha release in Wistar rats at 10 mg/kg oral dose | 14 | ALA1133554 | organism-based format | Scientific Literature | ||
16. | ALA820636 | B | Inhibition of [3H]rolipram binding to Wistar rat brain membranes | Rattus norvegicus | 8 | ALA1133554 | cell membrane format | Scientific Literature | |
17. | ALA1001309 | B | Inhibition of PDE4 | 27 | ALA1157355 | assay format | Scientific Literature |