| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA691955 | F | Anti-proliferative activity against human tumor cell line HT1080 | Homo sapiens | 9 | ALA1134990 | cell-based format | Scientific Literature | |
| 2. | ALA687677 | F | Inhibitory concentration against HT1080 cells proliferation | Homo sapiens | 24 | ALA1145900 | cell-based format | Scientific Literature | |
| 3. | ALA695135 | B | Inhibition of human histone deacetylase (mixture of HDAC1 and HDAC2) prepared from K562 erythroleukemia cells. | Homo sapiens | 24 | ALA1134990 | cell-based format | Scientific Literature | |
| 4. | ALA695140 | B | In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extract | 26 | ALA1148417 | protein format | Scientific Literature | ||
| 5. | ALA695141 | B | Inhibitory concentration against human histone deacetylase | Homo sapiens | 40 | ALA1145900 | protein format | Scientific Literature | |
| 6. | ALA711672 | F | Anti-proliferative activity against human tumor cell line MDA-435 | Homo sapiens | 8 | ALA1134990 | cell-based format | Scientific Literature | |
| 7. | ALA711678 | F | Inhibitory concentration against MDA-435 cells proliferation | 22 | ALA1145900 | cell-based format | Scientific Literature | ||
| 8. | ALA1838745 | B | Inhibition of HDAC8 assessed as substrate deacetylation using N-acetyl-L-Arg-LHis-L-Lys(epsilon-acetyl)-L-Lys(epsilon-acetyl)-coumarin as substrate preincubated for 15 mins measured after 20 mins by fluorescence assay | 1 | ALA1833881 | single protein format | Scientific Literature | ||
| 9. | ALA1838746 | B | Inhibition of Mycoplana ramosa acetylpolyamine amidohydrolase assessed as substrate deacetylation using L-Lys(epsilon-acetyl)-coumarin as substrate preincubated for 15 mins measured after 30 mins by fluorescence assay | Mycoplana ramosa | 1 | ALA1833881 | single protein format | Scientific Literature | |
| 10. | ALA1838751 | B | Inhibition of HDAC1/HDAC8 | 2 | ALA1833881 | protein format | Scientific Literature | ||
| 11. | ALA3801291 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as residual enzyme activity using fluorogenic Ac-LGK-ac-AMC as substrate for 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA3797051 | cell-based format | Scientific Literature | |
| 12. | ALA3801292 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as residual enzyme activity preincubated for 15 mins followed by addition of fluorogenic Ac-LGK-ac-AMC as substrate for 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA3797051 | cell-based format | Scientific Literature | |
| 13. | ALA3801293 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as residual enzyme activity preincubated for 30 mins followed by addition of fluorogenic Ac-LGK-ac-AMC as substrate for 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA3797051 | cell-based format | Scientific Literature | |
| 14. | ALA3801294 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as residual enzyme activity preincubated for 1 hr followed by addition of fluorogenic Ac-LGK-ac-AMC as substrate for 30 mins by fluorescence analysis | Homo sapiens | 3 | ALA3797051 | cell-based format | Scientific Literature | |
| 15. | ALA3802963 | B | Inhibition of recombinant human HDAC3/NCOR1 complex expressed in insect cells assessed as residual enzyme activity preincubated for 2 hrs followed by addition of fluorogenic Ac-LGK-ac-AMC as substrate for 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA3797051 | cell-based format | Scientific Literature | |
| 16. | ALA3802964 | B | Inhibition of recombinant His-tagged human HDAC1 expressed in insect cells assessed as hydrolase activity using fluorogenic Ac-LGK-ac-AMC as substrate measured after 60 mins by fluorescence analysis | Homo sapiens | 3 | ALA3797051 | cell-based format | Scientific Literature | |
| 17. | ALA3802965 | B | Inhibition of His-tagged recombinant human HDAC2 expressed in insect cells assessed as hydrolase activity using fluorogenic AC-LGK-ac-AMC as substrate measured after 60 mins by fluorescence analysis | Homo sapiens | 3 | ALA3797051 | cell-based format | Scientific Literature | |
| 18. | ALA3802966 | B | Inhibition of recombinant human HDAC8 expressed in Escherichia coli assessed as hydrolase activity using fluorogenic AC-LGK-tfa-AMC as substrate measured after 60 mins by fluorescence analysis | Homo sapiens | 3 | ALA3797051 | assay format | Scientific Literature | |
| 19. | ALA3802967 | B | Inhibition of His-tagged recombinant human HDAC6 expressed in insect cells assessed as hydrolase activity using fluorogenic AC-LGK-ac-AMC as substrate measured after 60 mins by fluorescence analysis | Homo sapiens | 3 | ALA3797051 | cell-based format | Scientific Literature | |
| 20. | ALA3802968 | B | Inhibition of N-terminal GST-tagged recombinant human HDAC4 assessed as hydrolase activity using fluorogenic Ac-AC-LGK-tfa-AMC-AMC as substrate measured after 60 mins by fluorescence analysis | Homo sapiens | 3 | ALA3797051 | single protein format | Scientific Literature |
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