# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA686013 | Binding | Glutathione peroxidase activity in V79 cells at 15 uM expressed as fold induction of GPx activity to control value | Cricetulus griseus | 1 | ALA1145854 | cell-based format | Scientific Literature | |
2. | ALA3372313 | Functional | Cytotoxicity against mouse CCL8 cells after 72 hrs by MTT assay | Mus musculus | 15 | ALA3351494 | cell-based format | Scientific Literature | |
3. | ALA3372314 | Functional | Cytotoxicity against human MDA-MB-435S cells after 72 hrs by MTT assay | Homo sapiens | 15 | ALA3351494 | cell-based format | Scientific Literature | |
4. | ALA3372315 | Functional | Cytotoxicity against human MES-SA cells after 72 hrs by MTT assay | Homo sapiens | 15 | ALA3351494 | cell-based format | Scientific Literature | |
5. | ALA3372316 | Functional | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay | Homo sapiens | 15 | ALA3351494 | cell-based format | Scientific Literature | |
6. | ALA3372317 | Functional | Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay | Homo sapiens | 16 | ALA3351494 | cell-based format | Scientific Literature | |
7. | ALA3372318 | Functional | Cytotoxicity against mouse MG-22A cells after 72 hrs by MTT assay | Mus musculus | 16 | ALA3351494 | cell-based format | Scientific Literature | |
8. | ALA3372319 | ADME | Cytotoxicity against mouse NIH/3T3 cells after 72 hrs by MTT assay | Mus musculus | 16 | ALA3351494 | cell-based format | Scientific Literature | |
9. | ALA3372869 | Toxicity | Acute toxicity in po dosed rat | Rattus norvegicus | 16 | ALA3351494 | organism-based format | Scientific Literature | |
10. | ALA1639719 | Toxicity | Toxicity in po dosed Swiss albino mouse | Mus musculus | 5 | ALA1629707 | organism-based format | Scientific Literature | |
11. | ALA1632796 | Toxicity | Hepatotoxicity in Swiss albino mouse assessed as infiltration of mononuclear cells at 1.2 mg/kg after 30 days by histopathology analysis | Mus musculus | 1 | ALA1629707 | organism-based format | Scientific Literature | |
12. | ALA1632797 | Toxicity | Nephrotoxicity in Swiss albino mouse assessed as infiltration of mononuclear cells at 1.2 mg/kg after 30 days by histopathology analysis | Mus musculus | 1 | ALA1629707 | organism-based format | Scientific Literature | |
13. | ALA1632804 | Functional | Increase of GSH level in Swiss albino mouse liver assessed per mg of protein at 1.2 mg/kg, po after 30 days (Rvb = 46.87+/-1.88 nmol) | Mus musculus | 1 | ALA1629707 | organism-based format | Scientific Literature | |
14. | ALA1632805 | Functional | Increase of GST level in Swiss albino mouse liver assessed as CDNB-GSH conjugate per mg of protein at 1.2 mg/kg, po after 30 days (Rvb = 95.66+/-4.0 nmol/min) | Mus musculus | 1 | ALA1629707 | organism-based format | Scientific Literature | |
15. | ALA1632806 | Toxicity | Toxicity in Swiss albino mouse assessed as hemoglobin level at 1.2 mg/kg, po after 30 days (Rvb = 12.56+/-0.43 gm/dL) | Mus musculus | 1 | ALA1629707 | organism-based format | Scientific Literature | |
16. | ALA1632807 | Toxicity | Hepatotoxicity in Swiss albino mouse assessed as TBARS production per mg of protein at 1.2 mg/kg, po after 30 days (Rvb = 0.26+/-0.02 nmol) | Mus musculus | 1 | ALA1629707 | organism-based format | Scientific Literature | |
17. | ALA1632808 | Toxicity | Hepatotoxicity in Swiss albino mouse assessed as plasma ALT level at 1.2 mg/kg, po after 30 days (Rvb = 66.00+/-4.18 U/mL) | Mus musculus | 1 | ALA1629707 | organism-based format | Scientific Literature | |
18. | ALA1632809 | Toxicity | Hepatotoxicity in Swiss albino mouse assessed as plasma AST level at 1.2 mg/kg, po after 30 days (Rvb = 179.00+/-4.18 U/mL) | Mus musculus | 1 | ALA1629707 | organism-based format | Scientific Literature | |
19. | ALA1632810 | Toxicity | Nephrotoxicity in Swiss albino mouse assessed as BUN level at 1.2 mg/kg, po after 30 days (Rvb = 21.57+/-0.92 mg/dL) | Mus musculus | 1 | ALA1629707 | organism-based format | Scientific Literature | |
20. | ALA1632811 | Toxicity | Nephrotoxicity in Swiss albino mouse assessed as serum creatinine level at 1.2 mg/kg, po after 30 days (Rvb = 9.40+/-0.48 mg/dL) | Mus musculus | 1 | ALA1629707 | organism-based format | Scientific Literature |