# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA677311 | B | Relative Binding Affinity for human estrogen receptor alpha expressed in CHO cells compared to Diethylstilbestrol Dimethyl Ether | Homo sapiens | 1 | ALA1145862 | cell-based format | Scientific Literature | |
2. | ALA3637770 | B | Transactivation of full length human PXR (unknown origin) transfected in human HepG2 cells at 10 uM after 18 hrs by luciferase reporter assay | Homo sapiens | 12 | ALA3632562 | cell-based format | Scientific Literature | |
3. | ALA3635223 | B | Transactivation of full length human PXR transfected in human HepG2 cells after 18 hrs by luciferase reporter assay relative to rifaximin | Homo sapiens | 2 | ALA3632562 | cell-based format | Scientific Literature | |
4. | ALA3635225 | F | Up regulation of full length PXR expression in human HepG2 cells at 10 uM after 18 hrs by quantitative real-time PCR analysis | Homo sapiens | 2 | ALA3632562 | cell-based format | Scientific Literature | |
5. | ALA3635226 | B | Transactivation of PXR in human HepG2 cells assessed as up regulation of CYP3A4 gene expression at 10 uM after 18 hrs by quantitative Real-time PCR analysis | Homo sapiens | 1 | ALA3632562 | cell-based format | Scientific Literature | |
6. | ALA3635229 | B | Transactivation of ERalpha (unknown origin) transfected in human HepG2 cells at 10 uM after 18 hrs by luciferase reporter assay relative to 17beta-estradiol | Homo sapiens | 3 | ALA3632562 | cell-based format | Scientific Literature | |
7. | ALA3635230 | B | Transactivation of ERRbeta (unknown origin) transfected in human HepG2 cells at 10 uM after 18 hrs by luciferase reporter assay relative to 17beta-estradiol | Homo sapiens | 3 | ALA3632562 | cell-based format | Scientific Literature | |
8. | ALA3635231 | B | Activity activity at ERalpha (unknown origin) transfected in human HepG2 cells assessed as increase in of 17beta-estradiol effect at 50 uM after 18 hrs by luciferase reporter assay | Homo sapiens | 3 | ALA3632562 | cell-based format | Scientific Literature | |
9. | ALA3635232 | B | Antagonist activity at ERRbeta (unknown origin) transfected in human HepG2 cells assessed as inhibition of genistein-induced effect at 50 uM after 18 hrs by luciferase reporter assay | Homo sapiens | 3 | ALA3632562 | cell-based format | Scientific Literature | |
10. | ALA4329825 | B | Inhibition of P-gp-mediated doxorubicin efflux in human Lucena 1 cells assessed as ratio of doxorubicin fluorescence intensity in presence of compound to doxorubicin fluorescence intensity in absence of compound at 25 uM preincubated for 1 hr followed by doxorubicin addition measured after 1 hr by flow cytometry | Homo sapiens | 22 | ALA4325923 | cell-based format | Scientific Literature | |
11. | ALA4329826 | B | Inhibition of P-gp-mediated doxorubicin efflux in human Lucena 1 cells assessed as ratio of doxorubicin fluorescence intensity in presence of compound to doxorubicin fluorescence intensity in absence of compound at 12.5 uM preincubated for 1 hr followed by doxorubicin addition measured after 1 hr by flow cytometry | Homo sapiens | 11 | ALA4325923 | cell-based format | Scientific Literature | |
12. | ALA4329827 | B | Inhibition of P-gp-mediated doxorubicin efflux in human Lucena 1 cells assessed as ratio of doxorubicin fluorescence intensity in presence of compound to doxorubicin fluorescence intensity in absence of compound at 6.25 uM preincubated for 1 hr followed by doxorubicin addition measured after 1 hr by flow cytometry | Homo sapiens | 11 | ALA4325923 | cell-based format | Scientific Literature | |
13. | ALA4329836 | B | Inhibition of P-gp-mediated doxorubicin efflux in human Lucena 1 cells preincubated for 1 hr followed by doxorubicin addition measured after 1 hr by flow cytometry | Homo sapiens | 7 | ALA4325923 | cell-based format | Scientific Literature | |
14. | ALA4329838 | F | Inhibition of doxorubicin efflux in human K562 cells at 25 uM preincubated for 1 hr followed by doxorubicin addition measured after 1 hr by flow cytometry | Homo sapiens | 8 | ALA4325923 | cell-based format | Scientific Literature |