| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3534703 | ADME | Activity of recombinant human CYP3A4 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with montelukast at 1 uM after 60 mins by LC-MS analysis | Homo sapiens | 2 | ALA3525951 | assay format | Scientific Literature | |
| 2. | ALA3534704 | ADME | Activity of recombinant human CYP2C9 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with montelukast at 1 uM after 60 mins by LC-MS analysis | Homo sapiens | 2 | ALA3525951 | assay format | Scientific Literature | |
| 3. | ALA3534705 | ADME | Activity of recombinant human CYP3A5 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with montelukast at 1 uM after 60 mins by LC-MS analysis | Homo sapiens | 2 | ALA3525951 | assay format | Scientific Literature | |
| 4. | ALA3534706 | ADME | Activity of recombinant human CYP2C19 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with montelukast at 1 uM after 60 mins by LC-MS analysis | Homo sapiens | 1 | ALA3525951 | assay format | Scientific Literature | |
| 5. | ALA3534708 | ADME | Activity of recombinant human CYP2C8 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with montelukast at 0.02 to 0.1 uM after 3 mins by LC-MS analysis | Homo sapiens | 2 | ALA3525951 | assay format | Scientific Literature | |
| 6. | ALA3533927 | ADME | Activity of recombinant human CYP2C8 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with montelukast at 0.02 to 1 uM after 60 mins by LC-MS analysis | Homo sapiens | 2 | ALA3525951 | assay format | Scientific Literature | |
| 7. | ALA3529512 | ADME | Drug level in human liver microsomes treated with montelukast at 0.02 to 0.4 uM preincubated for 3 mins followed by beta-NADPH addition by LC-MS analysis | Homo sapiens | 5 | ALA3525951 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!