| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3538229 | A | Activity of recombinant human CYP2D6 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 2. | ALA3538471 | A | Activity of recombinant human CYP3A4 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 3. | ALA3538473 | A | Activity of recombinant human CYP3A4 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis in presence of cytochrome b5 | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 4. | ALA3538475 | A | Activity of recombinant human CYP3A5 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 5. | ALA3537632 | A | Activity of recombinant human CYP2A6 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 5 | assay format | Scientific Literature |
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