# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3535538 | ADME | Blood plasma concentration in human treated with 100 mg of efavirenz administered every 4 hrs by UPLC-MS/MS analysis | Homo sapiens | 3 | ALA3525980 | cell-free format | Scientific Literature | |
2. | ALA3535539 | ADME | Seminal plasma concentration in human treated with 100 mg of efavirenz administered every 4 hrs by UPLC-MS/MS analysis | Homo sapiens | 3 | ALA3525980 | cell-free format | Scientific Literature | |
3. | ALA3535543 | ADME | Fraction unbound in human seminal plasma treated with 100 mg of efavirenz administered every 4 hrs by ultrafiltration method | Homo sapiens | 3 | ALA3525980 | assay format | Scientific Literature | |
4. | ALA3535545 | ADME | Blood plasma protein binding in human treated with 100 mg of efavirenz administered every 4 hrs by ultrafiltration method | Homo sapiens | 3 | ALA3525980 | cell-free format | Scientific Literature | |
5. | ALA3532722 | ADME | Seminal plasma protein binding in human treated with 100 mg of efavirenz administered every 4 hrs by ultrafiltration method | Homo sapiens | 3 | ALA3525980 | cell-free format | Scientific Literature | |
6. | ALA3533055 | ADME | Drug metabolism in human liver microsomes assessed as formation of metabolites with retention time of 1.92 mins at 20 uM by UPLC-MS/MS analysis | Homo sapiens | 3 | ALA3525980 | assay format | Scientific Literature | |
7. | ALA3533059 | ADME | Drug metabolism of the compound assessed as CYP2B6 (unknown origin)-mediated formation of metabolites with retention time of 1.92 mins at 5 uM by UPLC-MS/MS analysis | Homo sapiens | 3 | ALA3525980 | single protein format | Scientific Literature | |
8. | ALA3533060 | ADME | Drug metabolism of the compound assessed as CYP2C8 (unknown origin)-mediated formation of dihydroxylated metabolites with retention time of 1.92 mins at 5 uM by UPLC-MS/MS analysis | Homo sapiens | 2 | ALA3525980 | single protein format | Scientific Literature | |
9. | ALA3533061 | Functional | Antiviral activity against HIV1 expressing Env-green fluorescent fusion protein infected in PBMC assessed as inhibition of viral activity after 72 hrs by flow cytometry analysis | Human immunodeficiency virus 1 | 4 | ALA3525980 | organism-based format | Scientific Literature | |
10. | ALA3533063 | ADME | Ratio of drug level in seminal plasma to blood plasma in human treated with 100 mg of efavirenz administered every 4 hrs by UPLC-MS/MS analysis | Homo sapiens | 2 | ALA3525980 | cell-free format | Scientific Literature |