| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3539294 | Physicochemical | Retention time of the compound by LC-MS/MS method | 23 | ALA3526141 | small-molecule physicochemical format | Scientific Literature | ||
| 2. | ALA3539295 | ADME | Drug metabolism in human plasma treated with [14C]boceprevir assessed as ratio of drug level by LC-MS/MS method relative to boceprevir | Homo sapiens | 23 | ALA3526141 | cell-free format | Scientific Literature | |
| 3. | ALA3539296 | ADME | Drug metabolism in human liver microsomes treated with 5 uM [14C]boceprevir assessed as compound formation by LC-MS/FSA method relative to total [14C]boceprevir | Homo sapiens | 20 | ALA3526141 | assay format | Scientific Literature | |
| 4. | ALA3539297 | ADME | Drug metabolism in human liver microsomes treated with 20 uM [14C]boceprevir assessed as compound formation by LC-MS/FSA method relative to total [14C]boceprevir | Homo sapiens | 21 | ALA3526141 | assay format | Scientific Literature | |
| 5. | ALA3539298 | ADME | Drug metabolism assessed as human CYP3A4-mediated compound formation from 5 uM [14C]boceprevir after 120 mins by LC-MS/FSA method relative to total [14C]boceprevir | Homo sapiens | 21 | ALA3526141 | single protein format | Scientific Literature | |
| 6. | ALA3539299 | ADME | Drug metabolism assessed as human CYP3A4-mediated compound formation from 20 uM [14C]boceprevir after 120 mins by LC-MS/FSA method relative to total [14C]boceprevir | Homo sapiens | 22 | ALA3526141 | single protein format | Scientific Literature | |
| 7. | ALA3539300 | ADME | Drug metabolism assessed as human CYP3A5-mediated compound formation from 5 uM [14C]boceprevir after 120 mins by LC-MS/FSA method relative to total [14C]boceprevir | Homo sapiens | 21 | ALA3526141 | single protein format | Scientific Literature | |
| 8. | ALA3539301 | ADME | Drug metabolism assessed as human CYP3A5-mediated compound formation from 20 uM [14C]boceprevir after 120 mins by LC-MS/FSA method relative to total [14C]boceprevir | Homo sapiens | 22 | ALA3526141 | single protein format | Scientific Literature | |
| 9. | ALA3539302 | ADME | Drug metabolism assessed as human CYP2D6-mediated compound formation from 5 uM [14C]boceprevir after 120 mins by LC-MS/FSA method relative to total [14C]boceprevir | Homo sapiens | 21 | ALA3526141 | single protein format | Scientific Literature | |
| 10. | ALA3539303 | ADME | Drug metabolism assessed as human CYP2C19-mediated compound formation from 5 uM [14C]boceprevir after 120 mins by LC-MS/FSA method relative to total [14C]boceprevir | Homo sapiens | 21 | ALA3526141 | single protein format | Scientific Literature | |
| 11. | ALA3539304 | ADME | Drug metabolism assessed as human CYP21A2-mediated compound formation from 5 uM [14C]boceprevir after 120 mins by LC-MS/FSA method relative to total [14C]boceprevir | Homo sapiens | 22 | ALA3526141 | single protein format | Scientific Literature | |
| 12. | ALA3539305 | ADME | Drug metabolism assessed as human CYP21A1-mediated compound formation from 5 uM [14C]boceprevir after 120 mins by LC-MS/FSA method relative to total [14C]boceprevir | Homo sapiens | 22 | ALA3526141 | single protein format | Scientific Literature | |
| 13. | ALA3541892 | ADME | Drug metabolism assessed as human CYP2B6-mediated compound formation from 5 uM [14C]boceprevir after 120 mins by LC-MS/FSA method relative to total [14C]boceprevir | Homo sapiens | 22 | ALA3526141 | single protein format | Scientific Literature | |
| 14. | ALA3541893 | ADME | Drug metabolism assessed as human CYP4F3A-mediated compound formation from 5 uM [14C]boceprevir after 120 mins by LC-MS/FSA method relative to total [14C]boceprevir | Homo sapiens | 22 | ALA3526141 | single protein format | Scientific Literature |
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