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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA3528483 ADME Activity of mouse MDR1A expressed in pig LLC-PK1 cells assessed as efflux ratio of permeability from basolateral to apical side to apical to basolateral side at 1 uM after 2 hrs Mus musculus 2 ALA3525917 cell-based format Scientific Literature 2. ALA3528484 ADME Tmax in wild-type mouse at 3 mg/kg, po Mus musculus 1 ALA3525917 organism-based format Scientific Literature 3. ALA3528485 ADME Tmax in MDR1A/1B knock-out mouse at 3 mg/kg, po Mus musculus 1 ALA3525917 organism-based format Scientific Literature 4. ALA3528486 ADME Cmax in wild-type mouse at 3 mg/kg, po Mus musculus 1 ALA3525917 organism-based format Scientific Literature 5. ALA3528487 ADME Cmax in MDR1A/1B knock-out mouse at 3 mg/kg, po Mus musculus 1 ALA3525917 organism-based format Scientific Literature 6. ALA3528488 ADME AUC in wild-type mouse at 3 mg/kg, po Mus musculus 1 ALA3525917 organism-based format Scientific Literature 7. ALA3528489 ADME AUC in MDR1A/1B knock-out mouse at 3 mg/kg, po Mus musculus 1 ALA3525917 organism-based format Scientific Literature 8. ALA3528490 ADME Ratio of drug level in brain to plasma in wild-type mouse at 3 mg/kg, po Mus musculus 1 ALA3525917 organism-based format Scientific Literature 9. ALA3528491 ADME Ratio of drug level in brain to plasma in MDR1A/1B knock-out mouse at 3 mg/kg, po Mus musculus 1 ALA3525917 organism-based format Scientific Literature 10. ALA3528492 Physicochemical Solubility of the compound in phosphate buffered saline at pH 7 to 7.2 1 ALA3525917 small-molecule physicochemical format Scientific Literature 11. ALA3530904 ADME Half life in Sprague-Dawley rat at 1 mg/kg, iv Rattus norvegicus 1 ALA3525917 organism-based format Scientific Literature 12. ALA3530905 ADME AUC in Sprague-Dawley rat at 1 mg/kg, iv Rattus norvegicus 1 ALA3525917 organism-based format Scientific Literature 13. ALA3530906 ADME Clearance in Sprague-Dawley rat at 1 mg/kg, iv Rattus norvegicus 1 ALA3525917 organism-based format Scientific Literature 14. ALA3530907 ADME Tmax in cynomolgus monkey at 3 mg/kg, po Macaca fascicularis 1 ALA3525917 organism-based format Scientific Literature 15. ALA3530908 ADME Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv Rattus norvegicus 1 ALA3525917 organism-based format Scientific Literature 16. ALA3528775 ADME Tmax in Sprague-Dawley rat at 3 mg/kg, po Rattus norvegicus 1 ALA3525917 organism-based format Scientific Literature 17. ALA3528776 ADME Cmax in Sprague-Dawley rat at 3 mg/kg, po Rattus norvegicus 1 ALA3525917 organism-based format Scientific Literature 18. ALA3528777 ADME Half life in Sprague-Dawley rat at 3 mg/kg, po Rattus norvegicus 1 ALA3525917 organism-based format Scientific Literature 19. ALA3528778 ADME AUC in Sprague-Dawley rat at 3 mg/kg, po Rattus norvegicus 1 ALA3525917 organism-based format Scientific Literature 20. ALA3528779 ADME Oral bioavailability in Sprague-Dawley rat at 3 mg/kg Rattus norvegicus 1 ALA3525917 organism-based format Scientific Literature