# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3533671 | ADME | AUClast in C57BL/6N mouse treated with JM6 at 10 mg/kg, po administered as single dose via gavage by LC-MS/MS analysis | Mus musculus | 3 | ALA3526063 | organism-based format | Scientific Literature | |
2. | ALA3533672 | ADME | Cmax in C57BL/6N mouse treated with JM6 at 10 mg/kg, po administered as single dose via gavage by LC-MS/MS analysis | Mus musculus | 3 | ALA3526063 | organism-based format | Scientific Literature | |
3. | ALA3536662 | ADME | Inhibition of C57BL/6J mouse KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analysis | Mus musculus | 4 | ALA3526063 | single protein format | Scientific Literature | |
4. | ALA3536663 | ADME | Inhibition of Wistar rat KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analysis | Rattus norvegicus | 4 | ALA3526063 | single protein format | Scientific Literature | |
5. | ALA3536664 | ADME | Inhibition of human KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analysis | Homo sapiens | 4 | ALA3526063 | single protein format | Scientific Literature |