# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3540217 | ADME | Drug level in Sprague-Dawley rat liver microsomes treated with [14C]-rivoglitazone at 20 uM after 4 hrs by radio-HPLC/LC-MS/MS analysis in presence of UDPGA and UDPGA/SAM | Rattus norvegicus | 2 | ALA3526048 | assay format | Scientific Literature | |
2. | ALA3540218 | ADME | Drug level in cynomolgus monkey liver microsomes treated with [14C]-rivoglitazone at 20 uM after 4 hrs by radio-HPLC/LC-MS/MS analysis in presence of UDPGA and UDPGA/SAM | Macaca fascicularis | 2 | ALA3526048 | assay format | Scientific Literature | |
3. | ALA3540219 | ADME | Drug level in human liver microsomes treated with [14C]-rivoglitazone at 20 uM after 4 hrs by radio-HPLC/LC-MS/MS analysis in presence of UDPGA and UDPGA/SAM | Homo sapiens | 2 | ALA3526048 | assay format | Scientific Literature | |
4. | ALA3540244 | ADME | Drug level in monkey plasma treated with [14C]rivoglitazone assessed as ratio of molar basis AUC (0 to t) at 1 mg/kg, po administered via gavage by LC-MS/MS analysis | Macaca mulatta | 14 | ALA3525983 | organism-based format | Scientific Literature | |
5. | ALA3541357 | ADME | Activity of human UGT1A3 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with [14C]-rivoglitazone at 20 uM after 4 hrs by radio-HPLC/LC-MS/MS analysis in presence of NADPH-generating system/SAM | Homo sapiens | 2 | ALA3526048 | assay format | Scientific Literature | |
6. | ALA3541358 | ADME | Activity of human UGT2B7 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with [14C]-rivoglitazone at 20 uM after 4 hrs by radio-HPLC/LC-MS/MS analysis in presence of NADPH-generating system/SAM | Homo sapiens | 2 | ALA3526048 | assay format | Scientific Literature | |
7. | ALA3537605 | Physicochemical | Retention time of the compound by LC-MS/MS analysis | 21 | ALA3525983 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA3537607 | ADME | AUC (0 to t) in monkey plasma treated with rivoglitazone at 1 mg/kg, po administered via gavage by LC-MS/MS analysis | Macaca mulatta | 15 | ALA3525983 | organism-based format | Scientific Literature | |
9. | ALA3528816 | ADME | Drug level in rat hepatocytes treated with [14C]-rivoglitazone at 30 uM after 3 hrs by radio-HPLC/LC-MS/MS analysis in presence of UDPGA and UDPGA/SAM | Rattus norvegicus | 2 | ALA3526048 | cell-based format | Scientific Literature | |
10. | ALA3528817 | ADME | Drug level in monkey hepatocytes treated with [14C]-rivoglitazone at 30 uM after 3 hrs by radio-HPLC/LC-MS/MS analysis in presence of UDPGA and UDPGA/SAM | Macaca mulatta | 2 | ALA3526048 | cell-based format | Scientific Literature | |
11. | ALA3528818 | ADME | Drug level in human hepatocytes treated with [14C]-rivoglitazone at 30 uM after 3 hrs by radio-HPLC/LC-MS/MS analysis in presence of UDPGA and UDPGA/SAM | Homo sapiens | 2 | ALA3526048 | cell-based format | Scientific Literature | |
12. | ALA3530967 | Physicochemical | Retention time of the compound by LC-MS/MS analysis | 14 | ALA3526048 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA3530493 | ADME | Drug excretion in monkey urine treated with [14C]rivoglitazone at 1 mg/kg, po administered via gavage measured during 0 to 72 hrs by radio-HPLC analysis | Macaca mulatta | 14 | ALA3525983 | organism-based format | Scientific Literature | |
14. | ALA3530494 | ADME | Drug excretion in monkey feces treated with [14C]rivoglitazone at 1 mg/kg, po administered via gavage measured during 0 to 72 hrs by radio-HPLC analysis | Macaca mulatta | 14 | ALA3525983 | organism-based format | Scientific Literature | |
15. | ALA3530495 | ADME | Drug excretion in monkey urine/feces treated with [14C]rivoglitazone at 1 mg/kg, po administered via gavage measured during 0 to 72 hrs by radio-HPLC analysis | Macaca mulatta | 14 | ALA3525983 | organism-based format | Scientific Literature |