| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3537255 | A | Drug metabolism in human liver microsomes assessed as metabolite formation at 50 uM treated 15 mins after antibody addition measured after 20 mins by HPLC-RA analysis in presence of CYP2E1-specific monoclonal antibody | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 2. | ALA3537256 | A | Drug metabolism in human liver microsomes assessed as metabolite formation at 50 uM treated 15 mins after antibody addition measured after 20 mins by HPLC-RA analysis in presence of CYP3A4-specific monoclonal antibody | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 3. | ALA3537257 | A | Drug metabolism in human liver microsomes assessed as metabolite formation at 50 uM treated 15 mins after antibody addition measured after 20 mins by HPLC-RA analysis in presence of CYP4F2-specific polyclonal antibody | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 4. | ALA3537258 | A | Activity at human recombinant CYP4F2 expressed in baculovirus-infected BTI-TN-5B1-4 insect cell microsomes assessed as metabolite formation at 50 uM by HPLC-RA analysis in presence of anti-CYP4F2 | Homo sapiens | 1 | ALA3525920 | cell-based format | Scientific Literature | |
| 5. | ALA3535833 | A | Activity at human recombinant CYP4F3A expressed in baculovirus-infected BTI-TN-5B1-4 insect cell microsomes assessed as metabolite formation at 5 to 100 M after 30 mins by HPLC-RA analysis | Homo sapiens | 1 | ALA3525920 | cell-based format | Scientific Literature | |
| 6. | ALA3535834 | A | Activity at human recombinant CYP19 expressed in baculovirus-infected BTI-TN-5B1-4 insect cell microsomes assessed as metabolite formation at 5 to 100 uM after 30 mins by HPLC-RA analysis | Homo sapiens | 1 | ALA3525920 | cell-based format | Scientific Literature | |
| 7. | ALA3535835 | A | Activity at human recombinant CYP4F2 expressed in baculovirus-infected BTI-TN-5B1-4 insect cell microsomes assessed as metabolite formation after 15 mins by Eadie-Hofstee plot analysis | Homo sapiens | 1 | ALA3525920 | cell-based format | Scientific Literature | |
| 8. | ALA3535836 | A | Activity at human recombinant CYP4F2 expressed in baculovirus-infected BTI-TN-5B1-4 insect cell microsomes assessed as metabolite formation after 15 mins measured per nmol of P450 by Eadie-Hofstee plot analysis | Homo sapiens | 1 | ALA3525920 | cell-based format | Scientific Literature | |
| 9. | ALA3535837 | A | Activity at human recombinant CYP4F2 expressed in baculovirus-infected BTI-TN-5B1-4 insect cell microsomes assessed as intrinsic clearance for metabolite formation after 15 mins measured per nmol of P450 by Eadie-Hofstee plot analysis | Homo sapiens | 1 | ALA3525920 | cell-based format | Scientific Literature | |
| 10. | ALA3535838 | A | Drug metabolism in human liver microsomes assessed as total metabolite formation at 1 to 50 uM after 20 mins by HPLC-RA analysis in presence of CYP3A4 inhibitor ketoconazole | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 11. | ALA3535839 | A | Drug metabolism in human liver microsomes assessed as total metabolite formation at 1 uM after 20 mins by HPLC-RA analysis in presence of 10 uM CYP3A4 inhibitor ketoconazole | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 12. | ALA3535840 | A | Drug metabolism in human liver microsomes assessed as total metabolite formation at 1 to 50 uM after 20 mins by HPLC-RA analysis in presence of CYP3A4 mechanism-based inhibitor TAO and NADPH | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 13. | ALA3535841 | A | Drug metabolism in human liver microsomes assessed as total metabolite formation at 1 to 50 uM after 20 mins by HPLC-RA analysis in presence of irreversible CYP3A inhibitor azamulin | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 14. | ALA3535842 | A | Drug metabolism in human liver microsomes assessed as total metabolite formation at 1 to 50 uM after 20 mins by HPLC-RA analysis in presence of mechanism-based CYP1A2 inhibitor furafylline and NADPH | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 15. | ALA3535843 | A | Drug metabolism in human liver microsomes assessed as total metabolite formation at 1 to 50 uM after 20 mins by HPLC-RA analysis in presence of CYP2C8 inhibitor paclitaxel | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 16. | ALA3535844 | A | Drug metabolism in human liver microsomes assessed as total metabolite formation at 1 to 50 uM after 20 mins by HPLC-RA analysis in presence of CYP2C9 inhibitor sulfaphenazole | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 17. | ALA3535845 | A | Drug metabolism in human liver microsomes assessed as total metabolite formation at 1 to 50 uM after 20 mins by HPLC-RA analysis in presence of CYP2C19 inhibitor tranylcypromine | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 18. | ALA3535846 | A | Drug metabolism in human liver microsomes assessed as total metabolite formation at 1 to 50 uM after 20 mins by HPLC-RA analysis in presence of CYP2D6 inhibitor quinidine | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 19. | ALA3535847 | A | Drug metabolism in human liver microsomes assessed as total metabolite formation at 1 to 50 uM after 20 mins by HPLC-RA analysis in presence of mechanism-based CYP2E1 inhibitor DETC and NADPH | Homo sapiens | 1 | ALA3525920 | assay format | Scientific Literature | |
| 20. | ALA3535848 | A | Activity at human recombinant CYP4F2 expressed in baculovirus-infected BTI-TN-5B1-4 insect cell microsomes at 10 uM by HPLC-RA analysis in presence of CYP4F2 and CYP4F12 inhibitor ketoconazole | Homo sapiens | 1 | ALA3525920 | cell-based format | Scientific Literature |
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