| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3540947 | ADME | Drug level in rat urine treated with setileuton | Rattus norvegicus | 1 | ALA3526019 | tissue-based format | Scientific Literature | |
| 2. | ALA3540948 | ADME | Activity of CYP1A2 in rat liver microsomes assessed as enzyme mediated compound formation treated with 10 uM setileuton after 2 mins in presence of NADPH (Rvb = 8.10 +/- 2.26 nM) | Rattus norvegicus | 1 | ALA3526019 | assay format | Scientific Literature | |
| 3. | ALA3540949 | ADME | Activity of CYP1A2 in rat liver microsomes assessed as enzyme mediated compound formation treated with 10 uM setileuton after 5 mins in presence of NADPH (Rvb = 8.10 +/- 2.26 nM) | Rattus norvegicus | 1 | ALA3526019 | assay format | Scientific Literature | |
| 4. | ALA3540950 | ADME | Activity of CYP1A2 in rat liver microsomes assessed as enzyme mediated compound formation treated with 10 uM setileuton after 8 mins in presence of NADPH (Rvb = 8.10 +/- 2.26 nM) | Rattus norvegicus | 1 | ALA3526019 | assay format | Scientific Literature | |
| 5. | ALA3540951 | ADME | Activity of CYP1A2 in rat liver microsomes assessed as enzyme mediated compound formation treated with 10 uM setileuton after 10 mins in presence of NADPH (Rvb = 8.10 +/- 2.26 nM) | Rattus norvegicus | 1 | ALA3526019 | assay format | Scientific Literature | |
| 6. | ALA3540952 | ADME | Activity of CYP1A2 in rat liver microsomes assessed as enzyme mediated compound formation treated with 10 uM setileuton after 2 mins in absence of NADPH (Rvb = 1.93 +/- 0.40 nM) | Rattus norvegicus | 1 | ALA3526019 | assay format | Scientific Literature | |
| 7. | ALA3540953 | ADME | Activity of CYP1A2 in rat liver microsomes assessed as enzyme mediated compound formation treated with 10 uM setileuton after 5 mins in absence of NADPH (Rvb = 1.93 +/- 0.40 nM) | Rattus norvegicus | 1 | ALA3526019 | assay format | Scientific Literature | |
| 8. | ALA3540954 | ADME | Activity of CYP1A2 in rat liver microsomes assessed as enzyme mediated compound formation treated with 10 uM setileuton after 8 mins in absence of NADPH (Rvb = 1.93 +/- 0.40 nM) | Rattus norvegicus | 1 | ALA3526019 | assay format | Scientific Literature | |
| 9. | ALA3540955 | ADME | Activity of CYP1A2 in rat liver microsomes assessed as enzyme mediated compound formation treated with 10 uM setileuton after 10 mins in absence of NADPH (Rvb = 1.93 +/- 0.40 nM) | Rattus norvegicus | 1 | ALA3526019 | assay format | Scientific Literature | |
| 10. | ALA3530297 | ADME | Activity of rat recombinant CYP1A1 expressed in baculovirus-infected insect cells assessed as enzyme-mediated compound formation treated with setileuton at 10 uM preincubated for 3 mins measured after 30 mins in presence of 1 mM NADPH | Rattus norvegicus | 1 | ALA3526019 | cell-based format | Scientific Literature | |
| 11. | ALA3530298 | ADME | Activity of rat recombinant CYP1A2 expressed in baculovirus-infected insect cells assessed as enzyme-mediated compound formation treated with setileuton at 10 uM preincubated for 3 mins measured after 30 mins in presence of 1 mM NADPH | Rattus norvegicus | 1 | ALA3526019 | cell-based format | Scientific Literature | |
| 12. | ALA3530299 | ADME | Activity of rat recombinant CYP3A1 expressed in baculovirus-infected insect cells assessed as enzyme-mediated compound formation treated with setileuton at 10 uM preincubated for 3 mins measured after 30 mins in presence of 1 mM NADPH | Rattus norvegicus | 1 | ALA3526019 | cell-based format | Scientific Literature | |
| 13. | ALA3530300 | ADME | Activity of rat recombinant CYP3A2 expressed in baculovirus-infected insect cells assessed as enzyme-mediated compound formation treated with setileuton at 10 uM preincubated for 3 mins measured after 30 mins in presence of 1 mM NADPH | Rattus norvegicus | 1 | ALA3526019 | cell-based format | Scientific Literature | |
| 14. | ALA3530306 | ADME | Drug level in NADPH fortified rat liver microsomes treated with setileuton | Rattus norvegicus | 1 | ALA3526019 | assay format | Scientific Literature |
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