# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3535402 | A | Apparent intrinsic clearance assessed as ratio of Vmax to Km for human recombinant CYP2A6-mediated 17-hydroexemestane formation at 10 uM after 10 mins by Michaelis-Menten saturation curve analysis | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
2. | ALA3535403 | A | Apparent intrinsic clearance assessed as ratio of Vmax to Km for human recombinant CYP1A1-mediated 17-hydroexemestane formation at 10 uM after 10 mins by Michaelis-Menten saturation curve analysis | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
3. | ALA3535404 | A | Apparent intrinsic clearance assessed as ratio of Vmax to Km for human recombinant CYP4A11-mediated 17-hydroexemestane formation at 10 uM after 10 mins by Michaelis-Menten saturation curve analysis | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
4. | ALA3535416 | A | Drug metabolism assessed as human recombinant CYP19-mediated 17-hydroexemestane formation at 10 uM after 10 mins by Michaelis-Menten saturation curve analysis | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
5. | ALA3535417 | A | Drug metabolism assessed as human recombinant CYP1A2-mediated 17-hydroexemestane formation at 10 uM after 10 mins by Michaelis-Menten saturation curve analysis | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
6. | ALA3528184 | A | Drug metabolism assessed as human recombinant CYP3A5-mediated 17-hydroexemestane formation at 10 uM after 10 mins by Michaelis-Menten saturation curve analysis | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
7. | ALA3528185 | A | Drug metabolism assessed as human recombinant CYP2B6-mediated 17-hydroexemestane formation at 10 uM after 10 mins by Michaelis-Menten saturation curve analysis | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
8. | ALA3528379 | A | Drug metabolism assessed as human recombinant CYP2A6-mediated 17-hydroexemestane formation at 10 uM after 10 mins by Michaelis-Menten saturation curve analysis | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
9. | ALA3528380 | A | Drug metabolism assessed as human recombinant CYP1A1-mediated 17-hydroexemestane formation at 10 uM after 10 mins by Michaelis-Menten saturation curve analysis | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
10. | ALA3528381 | A | Drug metabolism assessed as human recombinant CYP4A11-mediated 17-hydroexemestane formation at 10 uM after 10 mins by Michaelis-Menten saturation curve analysis | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
11. | ALA3528395 | A | Drug metabolism assessed as human recombinant CYP1A1-mediated 17-hydroexemestane formation rate per pmol of enzyme at 10 uM after 10 mins | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
12. | ALA3528396 | A | Drug metabolism assessed as human recombinant CYP2A6-mediated 17-hydroexemestane formation rate per pmol of enzyme at 10 uM after 10 mins | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
13. | ALA3528397 | A | Drug metabolism assessed as human recombinant CYP4A11-mediated 17-hydroexemestane formation rate per pmol of enzyme at 10 uM after 10 mins | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
14. | ALA3528398 | A | Drug metabolism assessed as human recombinant CYP3A4-mediated 17-hydroexemestane formation rate per pmol of enzyme at 10 uM after 10 mins | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
15. | ALA3528399 | A | Drug metabolism assessed as human recombinant CYP3A5-mediated 17-hydroexemestane formation rate per pmol of enzyme at 10 uM after 10 mins | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
16. | ALA3528400 | A | Drug metabolism assessed as human recombinant CYP2B6-mediated 17-hydroexemestane formation rate per pmol of enzyme at 10 uM after 10 mins | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
17. | ALA3528401 | A | Drug metabolism assessed as human recombinant CYP2C9-mediated 17-hydroexemestane formation rate per pmol of enzyme at 10 uM after 10 mins | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
18. | ALA3528402 | A | Drug metabolism assessed as human recombinant CYP2C19-mediated 17-hydroexemestane formation rate per pmol of enzyme at 10 uM after 10 mins | Homo sapiens | 1 | ALA3525953 | single protein format | Scientific Literature | |
19. | ALA3530035 | A | Drug metabolism in human liver microsomes assessed as retention time treated with 300 uM of exemestane after 10 mins by HPLC with UV analysis | Homo sapiens | 2 | ALA3525953 | assay format | Scientific Literature | |
20. | ALA3530038 | A | Drug metabolism in human liver microsomes assessed as 17-hydroexemestane formation after 10 mins by Michaelis-Menten saturation curve analysis | Homo sapiens | 1 | ALA3525953 | assay format | Scientific Literature |