# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3537735 | A | Drug metabolism assessed as human recombinant UGT1A1-mediated compound formation treated with AMG 853 at 10 uM after 30 mins by LC-MS/MS analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA3537736 | A | Drug metabolism assessed as human recombinant UGT1A3-mediated compound formation treated with AMG 853 at 10 uM after 30 mins by LC-MS/MS analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA3537737 | A | Drug metabolism assessed as human recombinant UGT2B7-mediated compound formation treated with AMG 853 at 10 uM after 30 mins by LC-MS/MS analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
4. | ALA3537738 | A | Drug metabolism assessed as human recombinant UGT1A4-mediated compound formation treated with AMG 853 at 10 uM after 30 mins by LC-MS/MS analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA3537739 | A | Drug metabolism assessed as human recombinant UGT1A8-mediated compound formation treated with AMG 853 at 10 uM after 30 mins by LC-MS/MS analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA3538092 | A | Drug metabolism in human liver microsomes treated with AMG 853 after 45 mins by LC-MS/MS analysis in presence of UDPGA | Homo sapiens | 1 | assay format | Scientific Literature | ||
7. | ALA3538093 | A | Drug metabolism assessed as human recombinant UGT1A1-mediated compound formation treated with AMG 853 after 45 mins by LC-MS/MS analysis in presence of UDPGA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA3538094 | A | Drug metabolism assessed as human recombinant UGT1A3-mediated compound formation treated with AMG 853 after 45 mins by LC-MS/MS analysis in presence of UDPGA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
9. | ALA3538095 | A | Drug metabolism assessed as human recombinant UGT2B7-mediated compound formation treated with AMG 853 after 45 mins by LC-MS/MS analysis in presence of UDPGA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA3538282 | A | Drug metabolism in human liver microsomes assessed as CYP3A5*3/*3-mediated compound formation after 15 mins by LC-MS/MS analysis in presence of UDPGA | Homo sapiens | 1 | assay format | Scientific Literature | ||
11. | ALA3534368 | A | Drug metabolism in human liver microsomes assessed as CYP3A5*1/*1-compound formation after 15 mins by LC-MS/MS analysis in presence of UDPGA | Homo sapiens | 1 | assay format | Scientific Literature | ||
12. | ALA3534694 | A | Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 5 to 30 mins by LC-MS/MS analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
13. | ALA3534695 | A | Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate after 5 to 30 mins by LC-MS/MS analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
14. | ALA3531866 | A | Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 5 to 30 mins by LC-MS/MS analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
15. | ALA3531867 | A | Inhibition of CYP2C19 in human liver microsomes using (S)-Mephenytoin as substrate after 5 to 30 mins by LC-MS/MS analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
16. | ALA3531868 | A | Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 5 to 30 mins by LC-MS/MS analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
17. | ALA3531869 | A | Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate after 5 to 30 mins by LC-MS/MS analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
18. | ALA3531870 | A | Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 5 to 30 mins by LC-MS/MS analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
19. | ALA3531871 | A | Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate after 5 to 30 mins by LC-MS/MS analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
20. | ALA3532217 | A | Linear mixed inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6-hydroxylation after 20 mins by LC-MS/MS analysis | Homo sapiens | 1 | assay format | Scientific Literature |