# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3536560 | ADME | Drug metabolism assessed as human recombinant FMO3-mediated ER-879123 formation in presence of dog liver cytosolic fractions and NAD+ at 50 uM after 60 mins by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | tissue-based format | Scientific Literature | |
2. | ALA3536561 | ADME | Drug metabolism assessed as human recombinant FMO1-mediated ER-879123 formation in presence of dog liver cytosolic fractions and NAD+ at 50 uM after 60 mins by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | tissue-based format | Scientific Literature | |
3. | ALA3534038 | ADME | Drug metabolism in human liver S9 fraction assessed as ER-879123 formation at 50 uM after 60 mins in presence of NAD+ and carboxylesterase inhibitor BNPP by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | subcellular format | Scientific Literature | |
4. | ALA3534039 | ADME | Drug metabolism in 50 degC treated dog liver S9 fraction assessed as ER-879123 formation at 50 uM after 60 mins in absence of NAD+ by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3525952 | tissue-based format | Scientific Literature | |
5. | ALA3534040 | ADME | Drug metabolism in human liver S9 fraction assessed as ER-879123 formation at 50 uM after 60 mins in presence of NAD+ and FMO1 and FMO3 substrate/inhibitor methimazole by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | subcellular format | Scientific Literature | |
6. | ALA3534041 | ADME | Drug metabolism in dog liver S9 fraction assessed as ER-879123 formation at 50 uM after 60 mins in presence of NAD+ and FMO1 and FMO3 substrate/inhibitor methimazole by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3525952 | subcellular format | Scientific Literature | |
7. | ALA3534042 | ADME | Drug metabolism in dog liver S9 fraction assessed as ER-879123 formation at 50 uM after 60 mins in presence of NAD+ and carboxylesterase inhibitor BNPP by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3525952 | subcellular format | Scientific Literature | |
8. | ALA3534043 | ADME | Drug metabolism in dog liver S9 fraction assessed as ER-879123 formation at 50 uM after 60 mins in presence of NAD+ and alcohol dehydrogenase inhibitor 4-methylpyrazole by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3525952 | subcellular format | Scientific Literature | |
9. | ALA3534044 | ADME | Drug metabolism in dog liver microsomes assessed as ER-879123 formation at 50 uM after 60 mins in presence of NADPH by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3525952 | assay format | Scientific Literature | |
10. | ALA3534045 | ADME | Drug metabolism in rat liver microsomes assessed as ER-879123 formation at 50 uM after 60 mins in presence of NADPH by LC-MS/MS method | Rattus norvegicus | 1 | ALA3525952 | assay format | Scientific Literature | |
11. | ALA3534046 | ADME | Drug metabolism in human liver microsomes assessed as ER-879123 formation at 50 uM after 60 mins in presence of NADPH by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | assay format | Scientific Literature | |
12. | ALA3534047 | ADME | Drug metabolism in dog hepatocytes assessed as ER-879123 formation at 50 uM after 120 mins in presence of NADPH by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3525952 | cell-based format | Scientific Literature | |
13. | ALA3534048 | ADME | Drug metabolism in rat hepatocytes assessed as ER-879123 formation at 50 uM after 120 mins in presence of NADPH by LC-MS/MS method | Rattus norvegicus | 1 | ALA3525952 | cell-based format | Scientific Literature | |
14. | ALA3534049 | ADME | Drug metabolism in human hepatocytes assessed as ER-879123 formation at 50 uM after 120 mins in presence of NADPH by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | cell-based format | Scientific Literature | |
15. | ALA3531507 | ADME | Drug metabolism in dog liver S9 fraction assessed as ER-879123 formation at 50 uM after 60 mins in presence of NADP+ by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3525952 | subcellular format | Scientific Literature | |
16. | ALA3531508 | ADME | Drug metabolism in human liver S9 fraction assessed as ER-879123 formation at 50 uM after 60 mins in presence of NADP+ by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | subcellular format | Scientific Literature | |
17. | ALA3531515 | ADME | Drug metabolism in 50 degC treated human liver S9 fraction assessed as ER-879123 formation at 50 uM after 60 mins in absence of NAD+ by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | tissue-based format | Scientific Literature | |
18. | ALA3531516 | ADME | Drug metabolism assessed as human recombinant FMO5-mediated ER-879123 formation in presence of rat liver cytosolic fractions at 50 uM after 60 mins by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | tissue-based format | Scientific Literature | |
19. | ALA3531517 | ADME | Drug metabolism assessed as human recombinant FMO5-mediated ER-879123 formation in presence of dog liver cytosolic fractions at 50 uM after 60 mins by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | tissue-based format | Scientific Literature | |
20. | ALA3531518 | ADME | Drug metabolism assessed as human recombinant FMO5-mediated ER-879123 formation in presence of human liver cytosolic fractions at 50 uM after 60 mins by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | tissue-based format | Scientific Literature |