# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3536564 | ADME | Drug level in dog liver microsomes treated with 10 uM ER-879819 after 60 mins in presence of NADH by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3525952 | assay format | Scientific Literature | |
2. | ALA3536565 | ADME | Drug level in human liver microsomes treated with 10 uM ER-879819 after 60 mins in presence of NADH by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | assay format | Scientific Literature | |
3. | ALA3531399 | ADME | Drug level assessed as human recombinant FMO5-mediated compound formation from 10 uM ER-879819 in presence NADPH after 60 mins by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | single protein format | Scientific Literature | |
4. | ALA3531400 | ADME | Drug level assessed as human recombinant FMO5-mediated compound formation from 10 uM ER-879819 in presence NADH after 60 mins by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | single protein format | Scientific Literature | |
5. | ALA3531504 | ADME | Drug level in dog hepatocytes treated with 50 uM E7016 after 120 mins in presence of NADPH by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3525952 | cell-based format | Scientific Literature | |
6. | ALA3531505 | ADME | Drug level in rat hepatocytes treated with 50 uM E7016 after 120 mins in presence of NADPH by LC-MS/MS method | Rattus norvegicus | 1 | ALA3525952 | cell-based format | Scientific Literature | |
7. | ALA3531506 | ADME | Drug level in human hepatocytes treated with 50 uM E7016 after 120 mins in presence of NADPH by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | cell-based format | Scientific Literature | |
8. | ALA3531509 | ADME | Drug level in dog liver S9 fraction treated with 50 uM E7016 after 60 mins in presence of NAD+ by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3525952 | subcellular format | Scientific Literature | |
9. | ALA3531510 | ADME | Drug level in dog liver S9 fraction treated with 50 uM E7016 after 60 mins in presence of NADP+ by LC-MS/MS method | Canis lupus familiaris | 1 | ALA3525952 | subcellular format | Scientific Literature | |
10. | ALA3531511 | ADME | Drug level in human liver S9 fraction treated with 50 uM E7016 after 60 mins in presence of NAD+ by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | subcellular format | Scientific Literature | |
11. | ALA3531512 | ADME | Drug level in human liver S9 fraction treated with 50 uM E7016 after 60 mins in presence of NADP+ by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | subcellular format | Scientific Literature | |
12. | ALA3531513 | ADME | Drug level in dog liver S9 fraction treated with 50 uM E7016 after 60 mins in presence of NADP+ by LC-MS/MS method relative to in presence of NAD+ | Canis lupus familiaris | 1 | ALA3525952 | subcellular format | Scientific Literature | |
13. | ALA3531514 | ADME | Drug level in human liver S9 fraction treated with 50 uM E7016 after 60 mins in presence of NADP+ by LC-MS/MS method relative to in presence of NAD+ | Homo sapiens | 1 | ALA3525952 | subcellular format | Scientific Literature | |
14. | ALA3531519 | ADME | Drug metabolism assessed as human recombinant FMO5-mediated compound formation from 50 uM E7016 in presence of rat liver cytosolic fractions after 60 mins by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | tissue-based format | Scientific Literature | |
15. | ALA3531520 | ADME | Drug metabolism assessed as human recombinant FMO5-mediated compound formation from 50 uM E7016 in presence of human liver cytosolic fractions after 60 mins by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | tissue-based format | Scientific Literature | |
16. | ALA3531521 | ADME | Drug metabolism assessed as human recombinant FMO5-mediated compound formation from 50 uM E7016 in presence of dog liver cytosolic fractions after 60 mins by LC-MS/MS method | Homo sapiens | 1 | ALA3525952 | tissue-based format | Scientific Literature |