# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3541197 | B | Inhibition of SC5DL activity in human hepatocytes assessed as increase in lathosterol level per gram of protein by GC-MS analysis (Rvb = 47.7 ug) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA3541199 | B | Inhibition of DHCR7 activity in human hepatocytes assessed as increase in 7-dehydrocholesterol level per gram of protein by GC-MS analysis (Rvb = 16.3 ug) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA3541201 | B | Inhibition of HMGCR activity in human hepatocytes assessed as mevalonate formed per mg of protein at 100 uM by GC-MS analysis (Rvb = 69 9 pmol/min) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA3538720 | A | Effect on CYP3A4 in human hepatocytes assessed as nifedipine oxidation activity using nifedipine as substrate at 10 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA3538721 | A | Effect on CYP3A4 mRNA expression in human hepatocytes at 10 uM after 12 to 48 hrs by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA3539026 | B | Inhibition of DHCR14 activity in human hepatocytes assessed as increase in FF-MAS level per gram of protein by GC-MS analysis (Rvb = 0.7 ug) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA3539028 | B | Inhibition of DHCR24 activity in human hepatocytes assessed as increase in desmosterol level per gram of protein by GC-MS analysis (Rvb = 5.5 ug) | Homo sapiens | 1 | cell-based format | Scientific Literature |