| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3541197 | Binding | Inhibition of SC5DL activity in human hepatocytes assessed as increase in lathosterol level per gram of protein by GC-MS analysis (Rvb = 47.7 ug) | Homo sapiens | 1 | ALA3526087 | cell-based format | Scientific Literature | |
| 2. | ALA3541199 | Binding | Inhibition of DHCR7 activity in human hepatocytes assessed as increase in 7-dehydrocholesterol level per gram of protein by GC-MS analysis (Rvb = 16.3 ug) | Homo sapiens | 1 | ALA3526087 | cell-based format | Scientific Literature | |
| 3. | ALA3541201 | Binding | Inhibition of HMGCR activity in human hepatocytes assessed as mevalonate formed per mg of protein at 100 uM by GC-MS analysis (Rvb = 69 9 pmol/min) | Homo sapiens | 1 | ALA3526087 | cell-based format | Scientific Literature | |
| 4. | ALA3538720 | ADME | Effect on CYP3A4 in human hepatocytes assessed as nifedipine oxidation activity using nifedipine as substrate at 10 uM | Homo sapiens | 1 | ALA3526087 | cell-based format | Scientific Literature | |
| 5. | ALA3538721 | ADME | Effect on CYP3A4 mRNA expression in human hepatocytes at 10 uM after 12 to 48 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA3526087 | cell-based format | Scientific Literature | |
| 6. | ALA3539026 | Binding | Inhibition of DHCR14 activity in human hepatocytes assessed as increase in FF-MAS level per gram of protein by GC-MS analysis (Rvb = 0.7 ug) | Homo sapiens | 1 | ALA3526087 | cell-based format | Scientific Literature | |
| 7. | ALA3539028 | Binding | Inhibition of DHCR24 activity in human hepatocytes assessed as increase in desmosterol level per gram of protein by GC-MS analysis (Rvb = 5.5 ug) | Homo sapiens | 1 | ALA3526087 | cell-based format | Scientific Literature |
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