# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3536176 | ADME | Drug metabolism in cynomolgus monkey liver S9 fraction treated with 50 uM of lenvatinib up to 120 mins by HPLC analysis in presence of GSH and NADPH | Macaca fascicularis | 1 | ALA3526157 | subcellular format | Scientific Literature | |
2. | ALA3536177 | ADME | Drug metabolism in cynomolgus monkey liver S9 fraction treated with 50 uM of lenvatinib up to 120 mins by HPLC analysis in presence of GSH and absence of NADPH | Macaca fascicularis | 1 | ALA3526157 | assay format | Scientific Literature | |
3. | ALA3536182 | ADME | Drug metabolism in human liver S9 fraction treated with 50 uM of lenvatinib up to 120 mins by HPLC analysis in presence of GSH and NADPH | Homo sapiens | 1 | ALA3526157 | subcellular format | Scientific Literature | |
4. | ALA3536183 | ADME | Drug metabolism in human liver S9 fraction treated with 50 uM of lenvatinib up to 120 mins by HPLC analysis in presence of GSH and absence of NADPH | Homo sapiens | 1 | ALA3526157 | assay format | Scientific Literature | |
5. | ALA3536188 | ADME | Drug retention time in cynomolgus monkey treated with 30 mg/kg, po of [14C]lenvatinib administered on day 1, 2 and 4 by radio-LC/MS analysis | Macaca fascicularis | 7 | ALA3526157 | organism-based format | Scientific Literature | |
6. | ALA3534033 | ADME | Drug metabolism in Sprague-Dawley rat liver S9 fraction treated with 50 uM of lenvatinib up to 120 mins by HPLC analysis in presence of GSH and NADPH | Rattus norvegicus | 1 | ALA3526157 | subcellular format | Scientific Literature | |
7. | ALA3534034 | ADME | Drug metabolism in Sprague-Dawley rat liver S9 fraction treated with 50 uM of lenvatinib up to 120 mins by HPLC analysis in presence of GSH and absence of NADPH | Rattus norvegicus | 1 | ALA3526157 | assay format | Scientific Literature | |
8. | ALA3534115 | ADME | Drug metabolism in cynomolgus monkey treated with 30 mg/kg, po of [14C]lenvatinib administered on day 1, 2 and 4 by radio-LC/MS analysis | Macaca fascicularis | 6 | ALA3526157 | organism-based format | Scientific Literature |