| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3538229 | A | Activity of recombinant human CYP2D6 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 8 | ALA3526051 | assay format | Scientific Literature | |
| 2. | ALA3538231 | A | Activity of recombinant human CYP2E1 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 4 | ALA3526051 | assay format | Scientific Literature | |
| 3. | ALA3538471 | A | Activity of recombinant human CYP3A4 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 5 | ALA3526051 | assay format | Scientific Literature | |
| 4. | ALA3538473 | A | Activity of recombinant human CYP3A4 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis in presence of cytochrome b5 | Homo sapiens | 5 | ALA3526051 | assay format | Scientific Literature | |
| 5. | ALA3538475 | A | Activity of recombinant human CYP3A5 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 5 | ALA3526051 | assay format | Scientific Literature | |
| 6. | ALA3539820 | A | Activity of recombinant human CYP1A1 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 6 | ALA3526051 | assay format | Scientific Literature | |
| 7. | ALA3537628 | A | Activity of recombinant human CYP1A2 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 6 | ALA3526051 | assay format | Scientific Literature | |
| 8. | ALA3537630 | A | Activity of recombinant human CYP1B1 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 4 | ALA3526051 | assay format | Scientific Literature | |
| 9. | ALA3537632 | A | Activity of recombinant human CYP2A6 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 5 | ALA3526051 | assay format | Scientific Literature | |
| 10. | ALA3537636 | A | Activity of recombinant human CYP2C9 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 5 | ALA3526051 | assay format | Scientific Literature | |
| 11. | ALA3537638 | A | Activity of recombinant human CYP2C18 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 4 | ALA3526051 | assay format | Scientific Literature | |
| 12. | ALA3537640 | A | Activity of recombinant human CYP2C19 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis | Homo sapiens | 7 | ALA3526051 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!