| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3531667 | A | Activity of human recombinant CYP4F3B assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA3531668 | A | Activity of human recombinant CYP4F12 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA3531669 | A | Drug metabolism in human liver microsomes assessed as CYP3A4-mediated (3R,3aS,4S,4aR,7R,8aR,9aR)-7-amino-4-((E)-2-(5-(3-fluorophenyl)pyridin-2-yl)vinyl)-3-methyldecahydronaphtho[2,3-c]furan-1(3H)-one formation at 25 uM after 120 mins by LC-MS/MS analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 4. | ALA3531671 | A | Drug metabolism in human liver microsomes assessed as CYP2J2-mediated (3R,3aS,4S,4aR,7R,8aR,9aR)-7-amino-4-((E)-2-(5-(3-fluorophenyl)pyridin-2-yl)vinyl)-3-methyldecahydronaphtho[2,3-c]furan-1(3H)-one formation at 25 uM after 120 mins by LC-MS/MS analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA3531397 | A | Activity of human recombinant CYP1A1 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA3531398 | A | Activity of human recombinant CYP1A2 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3532124 | A | Activity of human recombinant CYP2A6 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3532125 | A | Activity of human recombinant CYP1B1 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA3532126 | A | Activity of human recombinant CYP2B6 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA3532127 | A | Activity of human recombinant CYP2C8 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA3532128 | A | Activity of human recombinant CYP2C9 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA3532129 | A | Activity of human recombinant CYP2C18 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA3532130 | A | Activity of human recombinant CYP2C19 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA3532131 | A | Activity of human recombinant CYP2D6 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA3532132 | A | Activity of human recombinant CYP2E1 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3532133 | A | Activity of human recombinant CYP3A5 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA3532134 | A | Activity of human recombinant CYP4A11 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA3532135 | A | Activity of human recombinant CYP4F2 assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA3532136 | A | Activity of human recombinant CYP4F3A assessed as enzyme-mediated drug metabolism treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA3530820 | A | Drug level in human intestine microsomes treated with 25 uM vorapaxar after 120 mins by LC-MS/MS analysis in presence of NADPH | Homo sapiens | 1 | assay format | Scientific Literature |
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