| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4316662 | A | Inhibition of UDPGDH in rat hepatocytes after 20 to 120 secs by UV/Vis spectrophotometric analysis | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
| 2. | ALA4316663 | F | Cytotoxicity against human REH cells assessed as reduction in cell viability after 48 hrs by Alamar Blue assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA4316664 | A | Inhibition of UGT1A in rat hepatocytes preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4316667 | A | Inhibition of UDPGDH in rat hepatocytes assessed as decrease in bilirubin monoglucuronide level at 5 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4316668 | A | Inhibition of UDPGDH in rat hepatocytes assessed as decrease in bilirubin diglucuronide level at 5 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4316669 | A | Inhibition of UDPGDH in rat hepatocytes assessed as increase in unconjugated bilirubin level at 5 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4316670 | A | Inhibition of UDPGDH in rat hepatocytes assessed as decrease in bilirubin monoglucuronide level at 10 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4316671 | A | Inhibition of UDPGDH in rat hepatocytes assessed as decrease in bilirubin diglucuronide level at 10 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4316672 | A | Inhibition of UDPGDH in rat hepatocytes assessed as increase in unconjugated bilirubin level at 10 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4316673 | A | Inhibition of UDPGDH in rat hepatocytes assessed as decrease in bilirubin monoglucuronide level at 5 to 10 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4316674 | A | Inhibition of UDPGDH in rat hepatocytes assessed as decrease in bilirubin diglucuronide level at 5 to 10 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4316675 | A | Inhibition of UDPGDH in rat hepatocytes assessed as decrease in bilirubin diglucuronide level at 10 uM after 45 mins in presence of UDPGA by HPLC analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4316677 | A | Inhibition of UGT1A in rat hepatocytes assessed as decrease in bilirubin monoglucuronide level at 75 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4316678 | A | Inhibition of UGT1A in rat hepatocytes assessed as decrease in bilirubin diglucuronide level at 75 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4316679 | A | Inhibition of UGT1A in rat hepatocytes assessed as increase in unconjugated bilirubin level at 75 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins by HPLC analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4316680 | A | Inhibition of UDPGDH in rat hepatocytes assessed as decrease in bilirubin monoglucuronide level at 10 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins in presence of regorafenib by HPLC analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4316681 | A | Inhibition of UDPGDH in rat hepatocytes assessed as decrease in bilirubin diglucuronide level at 10 uM preincubated for 2 mins followed by UDPGA addition measured after 45 mins in presence of regorafenib by HPLC analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4373842 | A | Inhibition of Streptococcus pyogenes UDPGDH expressed in Escherichia coli/rat liver microsome UGT-1A assessed as reduction in BDG production at 5 uM in presence of UDPGA by HPLC analysis | 1 | microsome format | Scientific Literature | |||
| 19. | ALA4373843 | A | Inhibition of Streptococcus pyogenes UDPGDH expressed in Escherichia coli/rat liver microsome UGT-1A assessed as reduction in BMG production at 5 uM in presence of UDPGA by HPLC analysis | 1 | microsome format | Scientific Literature | |||
| 20. | ALA4373844 | A | Inhibition of Streptococcus pyogenes UDPGDH expressed in Escherichia coli assessed as inhibitior constant by mesuring UDPGA production after 20 to 120 secs by HPLC analysis | Streptococcus pyogenes | 2 | assay format | Scientific Literature |
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