# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3784831 | F | Anticlonogenic activity against 129sv mouse APL blast cells assessed as inhibition of colony formation of cells at 0.25 uM measured after 7 days relative to control | Mus musculus | 9 | ALA3779820 | cell-based format | Scientific Literature | |
2. | ALA3782870 | B | Inhibition of KDM1A in human NB4 cells assessed as increase in GFI1B mRNA expression at biochemical IC50 measured after 24 hrs by RT-PCR analysis relative to control | Homo sapiens | 9 | ALA3779820 | cell-based format | Scientific Literature | |
3. | ALA3782872 | B | Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release preincubated for 15 mins followed by substrate addition measured for 12 mins by fluorescence-based microplate reader analysis | Homo sapiens | 14 | ALA3779820 | assay format | Scientific Literature | |
4. | ALA3782873 | B | Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assay | Homo sapiens | 14 | ALA3779820 | assay format | Scientific Literature | |
5. | ALA3782874 | B | Inhibition of human recombinant MAOB expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assay | Homo sapiens | 14 | ALA3779820 | assay format | Scientific Literature | |
6. | ALA3782875 | B | Inhibition of KDM1B (unknown origin) | Homo sapiens | 14 | ALA3779820 | single protein format | Scientific Literature | |
7. | ALA3782876 | B | Selectivity ratio of IC50 for human recombinant MAOA expressed in Pichia pastoris to IC50 for human recombinant KDM1A/CoREST expressed in Escherichia coli | Homo sapiens | 4 | ALA3779820 | assay format | Scientific Literature | |
8. | ALA3782877 | B | Inhibition of KDM1A in human NB4 cells assessed as increase in CD11b mRNA expression at biochemical IC50 measured after 24 hrs by RT-PCR analysis relative to control | Homo sapiens | 9 | ALA3779820 | cell-based format | Scientific Literature | |
9. | ALA3782878 | F | Anticlonogenic activity against human THP1 cells assessed as inhibition of colony formation of cells at 0.5 uM measured after 13 days relative to control | Homo sapiens | 9 | ALA3779820 | cell-based format | Scientific Literature | |
10. | ALA5159710 | B | Inhibition of recombinant human MAO-B using benzylamine as substrate | Homo sapiens | 1 | ALA5154758 | single protein format | Scientific Literature | |
11. | ALA5159740 | B | Inhibition of human LSD1 using H3K4Me1 peptide as substrate incubated for 60 min by peroxidase-coupled method | Homo sapiens | 1 | ALA5154758 | single protein format | Scientific Literature | |
12. | ALA5159741 | B | Inhibition of human LSD2 using H3K4Me2 peptide as substrate incubated for 60 min by peroxidase-coupled method | Homo sapiens | 1 | ALA5154758 | single protein format | Scientific Literature | |
13. | ALA5159742 | B | Inhibition of recombinant human MAO-A using kynuramine as substrate | Homo sapiens | 1 | ALA5154758 | single protein format | Scientific Literature |