# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA619238 | B | Inhibitory concentration to inhibit 5-lipoxygenase in the rat | 2 | single protein format | Scientific Literature | |||
2. | ALA620567 | A | Oral bioavailability was determined; range 49-102% | 1 | organism-based format | Scientific Literature | |||
3. | ALA876432 | A | Plasma half-life was determined; 0.5-17.7h | 1 | cell-free format | Scientific Literature | |||
4. | ALA630695 | A | Dissociation constant was determined In vitro in isolated guinea pig trachea after intraduodenal administration | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
5. | ALA632994 | P | Dissociation constant was determined | 1 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA666435 | B | Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lung | Cavia porcellus | 11 | assay format | Scientific Literature | ||
7. | ALA664834 | B | Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lung at 10 uM | Cavia porcellus | 19 | assay format | Scientific Literature | ||
8. | ALA666680 | B | Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]LTD4 | Cavia porcellus | 1 | single protein format | Scientific Literature | ||
9. | ALA666687 | B | Compound was evaluated for its ability to displace [3H]LTD4 from LTD4 receptor in guinea pig lung membranes | Cavia porcellus | 6 | cell membrane format | Scientific Literature | ||
10. | ALA663215 | B | Binding affinity against Cysteinyl leukotriene D4 receptor | 11 | protein format | Scientific Literature | |||
11. | ALA684754 | F | Activity against leukotriene D4-induced contraction of guinea pig trachea, in the presence of glutathione | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
12. | ALA685980 | F | Inhibition of Leukotriene D4 induced bronchoconstriction when compound was administered intraduodenally at a dose of 25 mg/kg in guinea pig | Cavia porcellus | 25 | organism-based format | Scientific Literature | ||
13. | ALA680881 | F | Inhibition of Leukotriene D4 induced bronchoconstriction when compound was administered perorally at a dose of 25 mg/kg in guinea pig | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
14. | ALA684588 | F | Inhibition of leukotriene D4 induced bronchoconstriction in anesthetized guinea pigs after aerosol administration as 1% solution; NT means not tested | Cavia porcellus | 5 | organism-based format | Scientific Literature | ||
15. | ALA685246 | F | Inhibition of leukotriene D4 induced bronchoconstriction in anesthetized guinea pigs after intravenous administration at a dose of 10 mg/kg | Cavia porcellus | 34 | organism-based format | Scientific Literature | ||
16. | ALA684320 | F | Inhibition of ovalbumin-induced bronchoconstriction when compound was administered intraduodenally at a dose of 10 mg/kg in guinea pig | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
17. | ALA879035 | F | Inhibition of ovalbumin-induced bronchoconstriction when compound was administered perorally at a dose of 25 mg/kg in guinea pig | Cavia porcellus | 4 | organism-based format | Scientific Literature | ||
18. | ALA688113 | F | Inhibition of leukotriene D4 induced bronchoconstriction in anesthetized guinea pigs after intravenous administration | Cavia porcellus | 12 | organism-based format | Scientific Literature | ||
19. | ALA688597 | F | Inhibitory dose of the intraduodenally administered compound (10 min before giving agonist) that produced a 50% inhibition of leukotriene D4 induced bronchoconstriction in guinea pigs | Cavia porcellus | 2 | organism-based format | Scientific Literature | ||
20. | ALA686369 | F | Inhibitory dose of the intraduodenally administered compound (10 min before giving agonist) that produced a 50% inhibition of ovalbumin induced bronchoconstriction in guinea pigs | Cavia porcellus | 2 | organism-based format | Scientific Literature |