# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3579719 | Binding | Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay | Homo sapiens | 52 | ALA3576865 | cell-based format | Scientific Literature | |
2. | ALA3579720 | Binding | Agonist activity at P2Y10 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay | Homo sapiens | 52 | ALA3576865 | cell-based format | Scientific Literature | |
3. | ALA3579721 | Binding | Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay | Homo sapiens | 52 | ALA3576865 | cell-based format | Scientific Literature | |
4. | ALA3579722 | Binding | Agonist activity at mouse P2Y10 receptor expressed in McA-RH7777 cells assessed as actin stress fiber formation at 1 uM after 30 mins by confocal microscopy | Mus musculus | 4 | ALA3576865 | cell-based format | Scientific Literature | |
5. | ALA4014236 | Binding | Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr | Mus musculus | 36 | ALA4011662 | cell-based format | Scientific Literature | |
6. | ALA4014237 | Binding | Intrinsic activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/iL assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr relative to O-(Hydroxy(((2R,3R)-2-(((3-(2-((3-phenoxybenzyl)oxy)phenyl)- propanoyl)oxy)methyl)tetrahydro-2H-pyran-3-yl)oxy)phosphoryl)- L-serine | Mus musculus | 30 | ALA4011662 | cell-based format | Scientific Literature | |
7. | ALA4014240 | Binding | Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr relative to control | Mus musculus | 30 | ALA4011662 | cell-based format | Scientific Literature |