# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3580188 | Functional | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 33592 after 16 hrs | Staphylococcus aureus | 16 | ALA3576840 | organism-based format | Scientific Literature | |
2. | ALA3580189 | Functional | Antimicrobial activity against methicillin-resistant Staphylococcus epidermidis RP62A after 16 hrs | Staphylococcus epidermidis | 16 | ALA3576840 | organism-based format | Scientific Literature | |
3. | ALA3580190 | Functional | Antimicrobial activity against Enterococcus faecalis ATCC 700802 after 16 hrs | Enterococcus faecalis | 16 | ALA3576840 | organism-based format | Scientific Literature | |
4. | ALA3580191 | Functional | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 16 hrs | Pseudomonas aeruginosa | 16 | ALA3576840 | organism-based format | Scientific Literature | |
5. | ALA3580192 | Functional | Antimicrobial activity against Escherichia ATCC 25922 after 16 hrs | Escherichia | 16 | ALA3576840 | organism-based format | Scientific Literature | |
6. | ALA3580193 | ADME | Induction of hemolysis in human RBCs incubated for 1 hr | Homo sapiens | 13 | ALA3576840 | cell-based format | Scientific Literature | |
7. | ALA3580194 | ADME | Cytotoxicity against mouse N2a cells assessed as cell viability after 12 hrs by MTT assay | Mus musculus | 2 | ALA3576840 | cell-based format | Scientific Literature | |
8. | ALA3580195 | Functional | Induction of membrane disruption in methicillin-resistant Staphylococcus aureus ATCC 33592 at 10 ug/ml incubated for 2 hrs by DAPI and propidium iodide staining based fluorescence microscopy | Staphylococcus aureus | 1 | ALA3576840 | organism-based format | Scientific Literature | |
9. | ALA3580196 | Functional | Induction of membrane disruption in Escherichia ATCC 25922 at 10 ug/ml incubated for 2 hrs by DAPI and propidium iodide staining based fluorescence microscopy | Escherichia | 1 | ALA3576840 | organism-based format | Scientific Literature | |
10. | ALA3580197 | Functional | Induction of cell aggregation of Escherichia ATCC 25922 at 10 ug/ml incubated for 2 hrs by DAPI and propidium iodide staining based fluorescence microscopy | Escherichia | 1 | ALA3576840 | organism-based format | Scientific Literature | |
11. | ALA3580198 | Functional | Bactericidal activity against methicillin-resistant Staphylococcus aureus ATCC 33592 at 12.5 to 50 ug/ml measured after 30 mins by colony count based time-kill assay | Staphylococcus aureus | 1 | ALA3576840 | organism-based format | Scientific Literature | |
12. | ALA3580199 | Functional | Bactericidal activity against Escherichia ATCC 25922 at 25 and 50 ug/ml measured after 1 hr by colony count based time-kill assay | Escherichia | 1 | ALA3576840 | organism-based format | Scientific Literature | |
13. | ALA3580200 | Functional | Bactericidal activity against Escherichia ATCC 25922 assessed as reduction bacterial colony count at 25 ug/ml measured after 10 mins to 2 hrs by colony count based time-kill assay | Escherichia | 1 | ALA3576840 | organism-based format | Scientific Literature | |
14. | ALA3580201 | Physicochemical | Stability in presence of 0.1 mg/ml pronase in 100 mM pH 7.8 ammonium bicarbonate buffer at 37 degC assessed as compound degradation after 18 hrs by HPLC method | 2 | ALA3576840 | small-molecule physicochemical format | Scientific Literature |