| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3578790 | B | Inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assessed as release of 4-methylumbelliferone measured for 10 mins by fluorescence assay | Onchocerca volvulus | 8 | tissue-based format | Scientific Literature | ||
| 2. | ALA3578794 | F | Mitochondrial uncoupling activity in HEK293T/17 cells at 50 uM after 30 mins by TMRE staining-based fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA3578795 | F | Antionchocerciasis activity against L3 larval stage of Onchocerca volvulus assessed as inhibition of parasite molting at 10 uM treated for 24 hrs prior to complete medium and PBMC addition measured after 6 days by inverted microscopic analysis | Onchocerca volvulus | 8 | organism-based format | Scientific Literature | ||
| 4. | ALA3578797 | F | Antionchocerciasis activity against L3 larval stage of Onchocerca volvulus assessed as inhibition of parasite molting at 1 uM treated for 24 hrs prior to complete medium and PBMC addition measured after 6 days by inverted microscopic analysis | Onchocerca volvulus | 3 | organism-based format | Scientific Literature | ||
| 5. | ALA3578798 | A | Drug uptake in late stage L4 Caenorhabditis elegans at 10 uM after 6 hrs by LC-MS analysis | Caenorhabditis elegans | 2 | organism-based format | Scientific Literature | ||
| 6. | ALA3578892 | A | Cytotoxicity against HEK293T/17 cells at 5 uM after 0.5 to 24 hrs by MTS assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!