| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3579351 | F | Antileishmanial activity against DsRed2 expressing Leishmania donovani promastigote assessed as parasite death after 48 hrs by flow cytometry | Leishmania donovani | 4 | organism-based format | Scientific Literature | ||
| 2. | ALA3579352 | F | Antileishmanial activity against DsRed2 expressing Leishmania donovani amastigotes assessed as parasite death after 48 hrs by flow cytometry | Leishmania donovani | 4 | organism-based format | Scientific Literature | ||
| 3. | ALA3579353 | A | Cytotoxicity against BALB/c mouse peritoneal macrophages after 48 hrs by MTT assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA3579354 | F | Selectivity index, ratio of CC50 for BALB/c mouse peritoneal macrophages to IC50 for DsRed2-Leishmania donovani amastigotes | 3 | assay format | Scientific Literature | |||
| 5. | ALA3579355 | A | Induction of NO production in DBA/2 mouse macrophages after 72 hrs by Griess assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA3579356 | F | Inhibition of IL6 production in DsRed2-Leishmania donovani promastigote infected in C57BL/6 mouse macrophages after 72 hrs by ELISA | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4353029 | F | Antitrypanosomal activity against Trypanosoma cruzi strain Y trypomastigotes maintained in Rhesus monkey LLC-MK1 cells assessed as decrease in trypomastigotes cell viability incubated for 24 hrs by resazurin dye based colorimetric assay | Trypanosoma cruzi | 26 | organism-based format | Scientific Literature | ||
| 8. | ALA4353031 | F | Antitrypanosomal activity against Trypanosoma cruzi amastigotes infected in BALB/c mouse peritoneal macrophages assessed as decrease in parasitic load with in the cell incubated for 48 hrs by Giemsa staining based light microscopy | Trypanosoma cruzi | 26 | organism-based format | Scientific Literature | ||
| 9. | ALA4353032 | A | Cytotoxicity against mouse NCTC-929 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Mus musculus | 26 | cell-based format | Scientific Literature | ||
| 10. | ALA4353033 | T | Selectivity index, ratio of CC50 for mouse NCTC-929 cells to IC50 for Trypanosoma cruzi amastigotes infected in BA;B/c mouse peritoneal macrophages | 10 | assay format | Scientific Literature | |||
| 11. | ALA4726502 | F | Cytotoxicity against mouse B16-F10 cells | Mus musculus | 29 | cell-based format | Scientific Literature | ||
| 12. | ALA4726503 | F | Cytotoxicity against human A2058 cells | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 13. | ALA4726504 | A | Cytotoxicity against human T75 cells | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 14. | ALA4726505 | U | Selectivity index, ratio for IC50 for human T75 cells to IC50 for human A2058 cells | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 15. | ALA5053677 | F | Antiinflammatory activity in BALB/c mouse model of LPS-induced acute respiratory distress syndrome assessed as reduction in neutrophils in BALF at 30 mg/kg administered 6 hrs after LPS-stimulation | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA5053679 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as reduction in LPS-induced IL-6 mRNA expression at 10 to 60 uM by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5053680 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as reduction in LPS-induced IL-1beta mRNA expression at 10 to 60 uM by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5053681 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as reduction in LPS-induced NO production at 10 to 60 uM incubated for 48 hrs by Griess reagent based assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5053682 | A | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at 10 to 60 uM measured after 48 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5053683 | T | Toxicity in BALB/c mouse model of LPS-induced acute respiratory distress syndrome assessed as reduction in body mass loss percentage at 30 mg/kg administered 6 hrs after LPS-stimulation | Mus musculus | 2 | organism-based format | Scientific Literature |
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