# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3583803 | B | In vitro inhibition of full length human MGAT2 transfected in FreeStyle293 cells assessed as dioleoylglycerol by RapidFire/MS assay | Homo sapiens | 25 | ALA3580631 | cell-based format | Scientific Literature | |
2. | ALA3583804 | P | 1-Octanol-phosphate buffer partition coefficient, log D of the compound at pH 7.4 by HPLC system | 24 | ALA3580631 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA3583805 | B | In vitro inhibition of full length human MGAT3 transfected in Sf-21 cells using [1-14C]oleoyl-CoA assessed as incorporation of radioactivity into lipid by TLC assay | Homo sapiens | 1 | ALA3580631 | cell-based format | Scientific Literature | |
4. | ALA3583806 | B | In vitro inhibition of full length human DGAT1 transfected in Sf-21 cells using [1-14C]oleoyl-CoA assessed as incorporation of radioactivity into lipid by TLC assay | Homo sapiens | 1 | ALA3580631 | cell-based format | Scientific Literature | |
5. | ALA3583909 | B | In vitro inhibition of full length human DGAT2 transfected in Sf-21 cells using [1-14C]oleoyl-CoA assessed as incorporation of radioactivity into lipid by TLC assay | Homo sapiens | 1 | ALA3580631 | cell-based format | Scientific Literature | |
6. | ALA3583910 | B | In vitro inhibition of full length human ACAT1 transfected in Sf-21 cells using [1-14C]oleoyl-CoA assessed as incorporation of radioactivity into lipid by TLC assay | Homo sapiens | 1 | ALA3580631 | cell-based format | Scientific Literature | |
7. | ALA3583911 | A | Intrinsic clearance in human liver microsomes after 30 mins by LC/MS/MS analysis | Homo sapiens | 1 | ALA3580631 | assay format | Scientific Literature | |
8. | ALA3583912 | A | Intrinsic clearance in rat liver microsomes after 30 mins by LC/MS/MS analysis | Rattus norvegicus | 1 | ALA3580631 | assay format | Scientific Literature | |
9. | ALA3583913 | A | AUC (0 to 8 hrs) in mouse at 1 mg/kg, po by cassette dosing assay | Mus musculus | 1 | ALA3580631 | organism-based format | Scientific Literature | |
10. | ALA3583914 | A | Total clearance in mouse at 0.1 mg/kg, iv by cassette dosing assay | Mus musculus | 1 | ALA3580631 | organism-based format | Scientific Literature | |
11. | ALA3583915 | A | Oral bioavailability in mouse at 1 mg/kg by cassette dosing assay | Mus musculus | 2 | ALA3580631 | organism-based format | Scientific Literature |