| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3582564 | F | Antiviral activity against Hepatitis B virus in HepG2.CW cells assessed as inhibition of viral DNA replication at 1 uM after 9 days by real-time FQ-PCR analysis | Hepatitis B virus | 12 | ALA3580594 | organism-based format | Scientific Literature | |
| 2. | ALA3582565 | A | Cytotoxicity against human HepG2.2.15 cells by MTT assay | Homo sapiens | 12 | ALA3580594 | cell-based format | Scientific Literature | |
| 3. | ALA3582566 | F | Antiviral activity against Hepatitis B virus in HepG2.2.15 cells assessed as inhibition of intracellular/extracellular viral DNA replication at 0.2 to 5 uM by real-time FQ-PCR analysis | Hepatitis B virus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 4. | ALA3582567 | F | Antiviral activity against Hepatitis B virus in HepG2.2.15 cells assessed as inhibition of intracellular/extracellular viral DNA replication after 3 to 9 days by real-time FQ-PCR analysis | Hepatitis B virus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 5. | ALA3582568 | T | Acute toxicity in KM mouse assessed as adverse effect at 200 mg/kg, iv suspended in normal saline | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 6. | ALA3582569 | T | Acute toxicity in KM mouse assessed as listlessness at 300 mg/kg, iv suspended in normal saline | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 7. | ALA3582570 | T | Acute toxicity in KM mouse assessed as death at 400 mg/kg, iv suspended in normal saline | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 8. | ALA3582571 | T | Acute toxicity in KM mouse assessed as morbidity at 3 g/kg, iv suspended in 0.5% CMC/Na solution after 14 days | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 9. | ALA3582572 | T | Acute toxicity in KM mouse assessed as mortality at 3 g/kg, iv suspended in 0.5% CMC/Na solution after 14 days | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 10. | ALA3582573 | T | Acute toxicity in KM mouse assessed as weight loss at 3 g/kg, iv suspended in 0.5% CMC/Na solution after 14 days | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 11. | ALA3582574 | T | Toxicity in KM mouse assessed as peripheral WBC number in blood per liter at 20 mg/kg, po single dose after 48 hrs (Rvb = 11.10 x 2.69/L x 10'-9 cells) | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 12. | ALA3582835 | T | Toxicity in KM mouse assessed as peripheral WBC number in blood per liter at 40 mg/kg, po single dose after 48 hrs (Rvb = 11.10 x 2.69/L x 10'-9) | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 13. | ALA3582836 | T | Toxicity in KM mouse assessed as peripheral WBC number in blood per liter at 80 mg/kg, po single dose after 48 hrs (Rvb = 11.10 x 2.69/L x 10'-9) | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 14. | ALA3582838 | T | Toxicity in KM mouse assessed as micronucleus frequency in bone marrow polychromatic erythrocyte at 20 mg/kg, po single dose after 48 hrs (Rvb = 2.20 +/- 0.84 %) | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 15. | ALA3582839 | T | Toxicity in KM mouse assessed as micronucleus frequency in bone marrow polychromatic erythrocyte at 40 mg/kg, po single dose after 48 hrs (Rvb = 2.20 +/- 0.84 %) | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 16. | ALA3582840 | T | Toxicity in KM mouse assessed as micronucleus frequency in bone marrow polychromatic erythrocyte at 80 mg/kg, po single dose after 48 hrs (Rvb = 2.20 +/- 0.84 %) | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 17. | ALA3582842 | T | Toxicity in KM mouse assessed as peripheral WBC number in blood per liter at 5 mg/kg/day, po 5 doses (Rvb = 7.47 +/- 33.77 /L x 10'-9 cells) | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 18. | ALA3582843 | T | Toxicity in KM mouse assessed as peripheral WBC number in blood per liter at 10 mg/kg/day, po 5 doses (Rvb = 7.47 +/- 33.77 /L x 10'-9 cells) | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 19. | ALA3582844 | T | Toxicity in KM mouse assessed as peripheral WBC number in blood per liter at 20 mg/kg/day, po 5 doses (Rvb = 7.47 +/- 33.77 /L x 10'-9 cells) | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature | |
| 20. | ALA3582846 | T | Toxicity in KM mouse assessed as micronucleus frequency in bone marrow polychromatic erythrocyte at 5 mg/kg, po single dose after 48 hrs (Rvb = 1.20 +/- 0.45 %) | Mus musculus | 1 | ALA3580594 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!