Drug uptake in brain of rhesus monkey at 89 +/- 3 MBq, iv administered as bolus dose for 1 min measured at 5 mins post wash out by MicroPET image analysis
Drug uptake in striatum of Wistar rat brain at 48.8 MBq, iv administered as bolus dose for 30 secs measured over 120 mins post injection by MicroPET image analysis
Drug uptake in thalamus of Wistar rat brain at 48.8 MBq, iv administered as bolus dose for 30 secs measured over 120 mins post injection by MicroPET image analysis
Drug uptake in cortex of Wistar rat brain at 48.8 MBq, iv administered as bolus dose for 30 secs measured over 120 mins post injection by MicroPET image analysis
Drug uptake in cerebellum of Wistar rat brain at 48.8 MBq, iv administered as bolus dose for 30 secs measured over 120 mins post injection by MicroPET image analysis
Drug uptake in thalamus of rhesus monkey brain at 89 +/- 3 MBq, iv administered as bolus dose for 1 min measured over 90 mins post injection by MicroPET image analysis
Drug uptake in striatum of rhesus monkey brain at 89 +/- 3 MBq, iv administered as bolus dose for 1 min measured over 90 mins post injection by MicroPET image analysis
Drug uptake in cortex of rhesus monkey brain at 89 +/- 3 MBq, iv administered as bolus dose for 1 min measured over 90 mins post injection by MicroPET image analysis
Drug uptake in cerebellum of rhesus monkey brain at 89 +/- 3 MBq, iv administered as bolus dose for 1 min measured over 90 mins post injection by MicroPET image analysis
Inhibition of full length recombinant human GSK-3alpha expressed in baculovirus infected insect Sf9 cells using GS-2 peptide as substrate assessed as 33P incorporation into substrate peptide after 30 mins by beta scintillation counting analysis in presence of [33P]gamma-ATP
Competitive inhibition of full length recombinant human GSK-3alpha expressed in baculovirus infected insect Sf9 cells using GS-2 peptide as substrate assessed as 33P incorporation into substrate peptide after 30 mins by beta scintillation counting analysis in presence of [33P]gamma-ATP