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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA3584796 Binding Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assay Rattus norvegicus 30 ALA3580575 cell-based format Scientific Literature 2. ALA3584797 Physicochemical Solubility in water 3 ALA3580575 small-molecule physicochemical format Scientific Literature 3. ALA3584942 Toxicity Toxicity in CD1(ICR) mouse assessed as survival at 6.67 mg/kg, ip bid for 3 weeks Mus musculus 1 ALA3580575 organism-based format Scientific Literature 4. ALA3584943 Toxicity Toxicity in CD1(ICR) mouse assessed as induction of weight gain at 6.67 mg/kg, ip bid for 3 weeks Mus musculus 1 ALA3580575 organism-based format Scientific Literature 5. ALA3584944 Toxicity Toxicity in CD1(ICR) mouse assessed as survival at 50 mg/kg, po bid for 3 weeks Mus musculus 1 ALA3580575 organism-based format Scientific Literature 6. ALA3584945 Toxicity Toxicity in CD1(ICR) mouse assessed as induction of weight gain at 50 mg/kg, po bid for 3 weeks Mus musculus 1 ALA3580575 organism-based format Scientific Literature 7. ALA3584946 Toxicity Toxicity in CD1(ICR) mouse assessed as survival at 50 mg/kg, ip qd for 3 weeks Mus musculus 1 ALA3580575 organism-based format Scientific Literature 8. ALA3584947 Toxicity Toxicity in CD1(ICR) mouse assessed as induction of weight gain at 50 mg/kg, ip qd for 3 weeks Mus musculus 1 ALA3580575 organism-based format Scientific Literature 9. ALA3584948 Toxicity Toxicity in CD1(ICR) mouse assessed as survival at 70 mg/kg, ip bid for 3 weeks Mus musculus 1 ALA3580575 organism-based format Scientific Literature 10. ALA3584949 Toxicity Toxicity in CD1(ICR) mouse assessed as induction of weight gain at 70 mg/kg, ip bid for 3 weeks Mus musculus 1 ALA3580575 organism-based format Scientific Literature 11. ALA3584950 ADME Tmax in CD1(ICR) mouse at 100 mg/kg, ip by LC-MS/MS method Mus musculus 1 ALA3580575 organism-based format Scientific Literature 12. ALA3584951 ADME Tmax in CD1(ICR) mouse at 100 mg/kg, ig by LC-MS/MS method Mus musculus 1 ALA3580575 organism-based format Scientific Literature 13. ALA3584952 ADME Drug elimination in CD1(ICR) mouse at 100 mg/kg, ip by LC-MS/MS method Mus musculus 1 ALA3580575 organism-based format Scientific Literature 14. ALA3584953 ADME Drug elimination in CD1(ICR) mouse at 100 mg/kg, ig by LC-MS/MS method Mus musculus 1 ALA3580575 organism-based format Scientific Literature 15. ALA3584954 Functional Antitumor activity against human WiDr cells xenografted in BALB/c mouse assessed as inhibition of tumor growth at 10 mg/kg, ip bid for 3 weeks dosed after tumor volume reached 100 mm3 Homo sapiens 1 ALA3580575 organism-based format Scientific Literature 16. ALA3584955 Functional Antitumor activity against human WiDr cells xenografted in BALB/c mouse assessed as inhibition of tumor growth at 50 mg/kg, po bid for 3 weeks dosed after tumor volume reached 100 mm3 Homo sapiens 1 ALA3580575 organism-based format Scientific Literature 17. ALA3584956 Functional Antitumor activity against human WiDr cells xenografted in BALB/c mouse assessed as inhibition of tumor growth at 100 mg/kg, po qid for 3 weeks dosed starting from day 6 following tumor inoculation Homo sapiens 1 ALA3580575 organism-based format Scientific Literature 18. ALA3582852 Functional Antitumor activity against human WiDr cells xenografted in BALB/c mouse assessed as inhibition of tumor growth at 50 mg/kg, ip bid for 3 weeks dosed starting from day 6 following tumor inoculation Homo sapiens 1 ALA3580575 organism-based format Scientific Literature