| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3583829 | B | Inhibition of human CYP17 expressed in COS7 cells incubated for 1 hr before 17-hydroxypregnenolone substrate addition by EIA method | Homo sapiens | 4 | ALA3580617 | cell-based format | Scientific Literature | |
| 2. | ALA3583830 | B | Inhibition of CYP19 (unknown origin) using MFC substrate incubated for 30 mins | Homo sapiens | 4 | ALA3580617 | single protein format | Scientific Literature | |
| 3. | ALA3583831 | B | Inhibition of human CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assay | Homo sapiens | 37 | ALA3580617 | cell-based format | Scientific Literature | |
| 4. | ALA3583832 | B | Inhibition of human CYP11B1 expressed in V79 cells incubated for 1 hr before 11-deoxycortisol substrate addition by HTRF-based assay | Homo sapiens | 37 | ALA3580617 | cell-based format | Scientific Literature | |
| 5. | ALA3583833 | B | Selectivity index, ratio of IC50 for human CYP11B1 to IC50 for human CYP11B2 | Homo sapiens | 37 | ALA3580617 | assay format | Scientific Literature | |
| 6. | ALA3583945 | B | Inhibition of human CYP21 expressed in COS7 cells incubated for 1 hr before 17-hydroxypregnenolone substrate addition by HTRF-based assay | Homo sapiens | 4 | ALA3580617 | cell-based format | Scientific Literature | |
| 7. | ALA3583946 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 4 | ALA3580617 | single protein format | Scientific Literature | |
| 8. | ALA3583949 | B | Selectivity index, ratio of IC50 for CYP19 (unknown origin) to IC50 for human CYP11B2 | Homo sapiens | 4 | ALA3580617 | assay format | Scientific Literature | |
| 9. | ALA3583950 | U | Selectivity index, ratio of IC50 for CYP3A4 (unknown origin) to IC50 for human CYP11B2 | Homo sapiens | 1 | ALA3580617 | assay format | Scientific Literature | |
| 10. | ALA3583951 | U | Selectivity index, ratio of IC50 for CYP2C9 (unknown origin) to IC50 for human CYP11B2 | Homo sapiens | 1 | ALA3580617 | assay format | Scientific Literature | |
| 11. | ALA3583952 | U | Selectivity index, ratio of IC50 for CYP2D6 (unknown origin) to IC50 for human CYP11B2 | Homo sapiens | 1 | ALA3580617 | assay format | Scientific Literature | |
| 12. | ALA3583956 | A | Fraction unbound in rhesus monkey plasma at 2.5 mM incubated for 4 hrs by equilibrium dialysis and LC/MS method | Macaca mulatta | 3 | ALA3580617 | cell-free format | Scientific Literature | |
| 13. | ALA3583957 | A | Intrinsic clearance in rhesus monkey liver microsomes at 0.3 mM incubated for 10 mins before NADPH addition by LC/MS method | Macaca mulatta | 3 | ALA3580617 | assay format | Scientific Literature | |
| 14. | ALA3583958 | A | Oral bioavailability in rhesus monkey at 1 mg/kg by LC-MS/MS method | Macaca mulatta | 3 | ALA3580617 | organism-based format | Scientific Literature | |
| 15. | ALA3583959 | A | Dose normalized AUC in rhesus monkey at 1 mg/kg, po or 0.5 mg/kg, iv by LC-MS/MS method | Macaca mulatta | 3 | ALA3580617 | organism-based format | Scientific Literature | |
| 16. | ALA3583960 | A | Plasma clearance in rhesus monkey at 1 mg/kg, po or 0.5 mg/kg, iv by LC-MS/MS method | Macaca mulatta | 3 | ALA3580617 | organism-based format | Scientific Literature | |
| 17. | ALA3583962 | B | Inhibition of rhesus monkey CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assay | Macaca mulatta | 5 | ALA3580617 | cell-based format | Scientific Literature | |
| 18. | ALA3583963 | B | Inhibition of rat CYP11B2 expressed in V79 cells incubated for 1 hr before 11-deoxycorticosterone substrate addition by HTRF-based assay | Rattus norvegicus | 5 | ALA3580617 | cell-based format | Scientific Literature |
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