# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3588533 | Functional | Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA3585245 | cell-based format | Scientific Literature | |
2. | ALA3588534 | Functional | Antiproliferative activity against human SAS cells incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA3585245 | cell-based format | Scientific Literature | |
3. | ALA3588535 | Functional | Antiproliferative activity against human SKHep cells incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA3585245 | cell-based format | Scientific Literature | |
4. | ALA3588536 | Functional | Antiproliferative activity against human AGS cells incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA3585245 | cell-based format | Scientific Literature | |
5. | ALA3588537 | Functional | Antiproliferative activity against human 786-O cells incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA3585245 | cell-based format | Scientific Literature | |
6. | ALA3588538 | Functional | Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA3585245 | cell-based format | Scientific Literature | |
7. | ALA3588539 | Functional | Antiproliferative activity against human H1299 cells incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA3585245 | cell-based format | Scientific Literature | |
8. | ALA3588540 | Functional | Antiproliferative activity against human Detroit 551 cells incubated for 72 hrs by MTT assay | Homo sapiens | 22 | ALA3585245 | cell-based format | Scientific Literature | |
9. | ALA3588541 | Binding | Induction of DNA intercalation of negative supercoiled Escherichia coli pBR322 DNA at 10 uM incubated for 12 hrs by ethidium bromide staining based DNA mobility assay | Escherichia coli | 2 | ALA3585245 | nucleic acid format | Scientific Literature | |
10. | ALA3588543 | Functional | Induction of DNA damage in human H1299 cells at 5 uM incubated for 24 hrs by single cell electrophoresis-based alkaline comet assay | Homo sapiens | 1 | ALA3585245 | cell-based format | Scientific Literature | |
11. | ALA3588544 | Functional | Induction of apoptosis in human H1299 cells assessed as increase in PARP cleavage at 1 to 10 uM incubated for 24 hrs by Western blotting method | Homo sapiens | 1 | ALA3585245 | cell-based format | Scientific Literature | |
12. | ALA3586801 | Functional | Induction of apoptosis in human H1299 cells assessed as increase in BAX cleavage at 1 to 10 uM incubated for 24 hrs by Western blotting method | Homo sapiens | 1 | ALA3585245 | cell-based format | Scientific Literature | |
13. | ALA3586802 | Functional | Induction of apoptosis in human H1299 cells assessed as increase in caspase-3 activation at 1 to 10 uM incubated for 24 hrs by Western blotting method | Homo sapiens | 1 | ALA3585245 | cell-based format | Scientific Literature | |
14. | ALA3586803 | Functional | Induction of apoptosis in human H1299 cells assessed as increase in caspase-7 activation at 1 to 10 uM incubated for 24 hrs by Western blotting method | Homo sapiens | 1 | ALA3585245 | cell-based format | Scientific Literature | |
15. | ALA3586804 | Functional | Induction of apoptosis in human H1299 cells assessed as decrease in Bcl2 expression at 1 to 10 uM incubated for 24 hrs by Western blotting method | Homo sapiens | 1 | ALA3585245 | cell-based format | Scientific Literature | |
16. | ALA3586805 | Functional | Reduction in HDAC6 protein expression in human H1299 cells at 1 to 10 uM incubated for 24 hrs by Western blotting method | Homo sapiens | 1 | ALA3585245 | cell-based format | Scientific Literature | |
17. | ALA3586806 | Functional | Reduction in SIRT1 protein expression in human H1299 cells at 1 to 10 uM incubated for 24 hrs by Western blotting method | Homo sapiens | 1 | ALA3585245 | cell-based format | Scientific Literature | |
18. | ALA3586807 | Functional | Reduction in FOXO3a protein expression in human H1299 cells at 1 to 10 uM incubated for 24 hrs by Western blotting method | Homo sapiens | 1 | ALA3585245 | cell-based format | Scientific Literature | |
19. | ALA3586808 | Functional | Reduction in p-Akt protein expression in human H1299 cells at 1 to 10 uM incubated for 24 hrs by Western blotting method | Homo sapiens | 1 | ALA3585245 | cell-based format | Scientific Literature | |
20. | ALA3586809 | Functional | Reduction in PTEN protein expression in human H1299 cells at 1 to 10 uM incubated for 24 hrs by Western blotting method | Homo sapiens | 1 | ALA3585245 | cell-based format | Scientific Literature |