| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3587905 | B | Inhibition of PTP1B in mouse 3T3L1 cells assessed as stimulation of 2-NBDG uptake preincubated for 24 hrs followed by 2-NBDG addition measured after 30 mins by fluorescence reader analysis | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 2. | ALA3587906 | B | Inhibition of PTP1B in mouse 3T3L1 cells assessed as stimulation of 2-NBDG uptake at 10 uM preincubated for 24 hrs followed by 2-NBDG addition measured after 30 mins by fluorescence reader analysis relative to control | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA3587907 | A | Cytotoxicity against mouse 3T3L1 cells assessed as inhibition of cell viability at 5 to 10 uM after 48 hrs by MTT assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 4. | ALA3587908 | B | Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microplate reader analysis | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 5. | ALA3587976 | B | Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by Lineweaver-Burk/Dixon plot analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 6. | ALA4195640 | B | Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluorescence assay | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 7. | ALA4195642 | F | Cytotoxicity against human MGC803 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 8. | ALA4195643 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 9. | ALA4195644 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 10. | ALA4195645 | F | Cytotoxicity against human T24 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 11. | ALA4195646 | B | Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluorescence assay | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 12. | ALA4195647 | B | Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluorescence assay | Homo sapiens | 13 | single protein format | Scientific Literature |
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