# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3587233 | B | Inhibition of human recombinant PDE4D3 expressed in baculoviral system using cAMP as substrate at 10 uM by fluorescence polarization assay relative to control | Homo sapiens | 9 | assay format | Scientific Literature | ||
2. | ALA3587234 | B | Inhibition of human recombinant PDE4D3 expressed in baculoviral system using cAMP as substrate by fluorescence polarization assay | Homo sapiens | 9 | assay format | Scientific Literature | ||
3. | ALA3587235 | B | Inhibition of human recombinant PDE4A4 expressed in baculoviral system using cAMP as substrate at 10 uM by fluorescence polarization assay relative to control | Homo sapiens | 10 | assay format | Scientific Literature | ||
4. | ALA3587236 | B | Inhibition of human recombinant PDE4B2 expressed in baculoviral system using cAMP as substrate at 10 uM by fluorescence polarization assay relative to control | Homo sapiens | 10 | assay format | Scientific Literature | ||
5. | ALA3587237 | B | Inhibition of human recombinant PDE4C2 expressed in baculoviral system using cAMP as substrate at 10 uM by fluorescence polarization assay relative to control | Homo sapiens | 10 | assay format | Scientific Literature | ||
6. | ALA3587238 | A | Cytotoxicity against human HTLA-230 cells at 100 uM after 24 hrs by lactate dehydrogenase release assay (Rvb = 0.67 +/- 0.24%) | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
7. | ALA3587240 | T | Genotoxicity in human HTLA-230 cells assessed as gamma-H2AX production at 100 uM after 24 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature |